摘要
目的:常规体外试管法与分光光度法在中药注射剂溶血检查中的应用比较。方法:通过吸收波长、离心转速及温育时间的研究,建立了分光光度法测定溶血率的方法,并与常规体外试管法进行了3种中药注射剂溶血试验的结果对比。结果:分光光度法可以定量地测定中药注射剂的溶血程度,较常规体外试管法更能准确地判断药品的质量。结论:建议对于中药注射剂应使用分光光度法评价其溶血程度。
Objective： To compare the application of routine test tube method in vitro and Spectrophotometric method in traditional Chinese medicine injections. Method： A spectrophotometrie method for hemolysis ratio of traditional Chinese medicine injections was established by the study of absorption wavelength, centrifugal speed and incubation time. Hemolysis ratio results of three traditional Chinese medicine injections were compared by the spectrophotometrie method and the routine test tube method in vitro. Results： The Hemolysis ratio can be determined quantitatively by the speetrophotometric method and the quality of drug can be estimated more accurate- ly than by the routine test tube method in vitro. Conclusion： Spectrophotometrie method should be used in evaluation of Hemolysis degree of traditional Chinese medicine injections.
出处
《中国药品标准》
CAS
2011年第3期216-219,共4页
Drug Standards of China
关键词
中药注射剂
常规体外试管法
分光光度法
溶血率
traditional Chinese medicine injections
routine test tube method in vitro
spectrophotometric method
hemolysis ratio
