摘要
目的:比较胺碘酮与利多卡因治疗急性心肌梗死(AMI)并发室颤的临床疗效及安全性。方法:将我院2009年11月~2010年12月收治的50例AMI并室颤患者随机分为利多卡因组与胺碘酮组,每组25例,利多卡因组给予静脉滴注利多卡因治疗;胺碘酮组给予胺碘酮治疗,比较两种治疗的临床疗效及不良反应。结果:胺碘酮组的有效率明显高于利多卡因组;胺碘酮组的复发率明显低于利多卡因组;胺碘酮组的不良反应发生率明显低于利多卡因组(P<0.05)。结论:胺碘酮治疗急性心肌梗死并发室颤的临床疗效优于利多卡因,不良反应少,值得推广使用。
Objective:To compare the clinical efficacy and safety of Amiodarone with Lidocaine in acute myocardial infarction(AMI) complicated by ventricular fibrillation.Methods:50 patients with AMI and ventricular fibrillation in our hospital from November 2009 to December 2010 were randomly divided into Lidocaine group and the Amiodarone group,each 25 cases,Lidocaine group were given intravenous Lidocaine;Amiodarone group were given Amiodarone treatment,compared the clinical efficacy and adverse reactions after treatment.Results:The effective rate of Amiodarone group was significantly higher than Lidocaine group;the recurrence rate and the incidence of adverse reactions were significantly lower than the Lidocaine group(P0.05).Conclusion:Clinical efficacy of Amiodarone treatment in AMI complicated by ventricular fibrillation is better than lidocaine,with less adverse reactions,and it is worthy of application.
出处
《中国医药导报》
CAS
2011年第19期76-77,共2页
China Medical Herald
关键词
碘胺酮
利多卡因
急性心肌梗死
室颤
Amiodarone
Lidocaine
Acute myocardial infarction
Ventricular fibrillation