摘要
目的在丝虫病防治工作薄弱地区搜索残存传染源,为消除丝虫病后的监测工作提供科学依据。方法通过查阅历史资料,与专业人员座谈和实地查访等方式,确定丝虫病防治工作重点地区行政村,对10岁及以上居民进行丝虫特异IgG4抗体检测,阳性者采用ICT卡检测丝虫循环抗原。同时采制厚血膜,检查微丝蚴。结果确定恩施市、利川市、咸丰县、宣恩县和蕲春县等5县（市）8乡镇9个村为防治工作重点地区行政村。抽查村防治前人群平均微丝蚴率0.87%~6.62%,防治后微丝蚴率0~1.02%;检测人群丝虫特异抗体IgG4阳性率0.05%,阳性者ICT检测和病原学检测均阴性。结论湖北省丝虫病防治成果巩固,内源性传染源存在可能性极小,应重点加强流动人口的管理和监测。
Objective To search for remaining sources of infection in areas with limited efforts to prevent and control filariasis so as to provide a scientific basis for filariasis surveillance after its elimination.Methods Villages in key areas were selected as study sites based on a search of historical data,discussions with experts,and site visits.The level of anti-filarial antibodies was detected by testing for filaria-specific IgG4 in individuals age 10 and over at the study sites.ICT was used to detect circulating filarial antigen and thick blood films were used to detect microfilaria in individuals who tested positive.Results Study sites were 9 villages and 8 towns in the City of Enshi,Xuanen County,the City of Lichuan,Xianfeng County,and Qichun County.The average rate of microfilaria was 0.87%-6.62% before control measures and 0-1.02% afterwards.Filaria-specific IgG4 antibodies were detected at a rate of 0.05%.ICT results and pathogen detection were both negative for individuals who tested positive.Conclusion Filariasis control has proven effective in Hubei Province.Endogenous sources of infection are rather unlikely,so the management and monitoring of the migrant population should be enhanced.
出处
《中国病原生物学杂志》
CSCD
2011年第6期452-454,共3页
Journal of Pathogen Biology
关键词
丝虫病
传染源
重点地区
调查报告
Filariasis
infection source
key areas
investigation report
