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2种质子泵抑制剂分别联合克拉霉素和阿莫西林治疗胃溃疡的疗效对比观察 被引量:3

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摘要 目的比较埃索美拉唑和奥美拉唑分别联合克拉霉素和阿莫西林治疗胃溃疡的临床疗效。方法选择确诊为胃溃疡的门诊及住院患者92例,随机分为A组和B组,各46例。A组采用埃索美拉唑联合克拉霉素和阿莫西林治疗,B组采用奥美拉唑联合克拉霉素和阿莫西林治疗,治疗4周后比较2组总有效率、Hp清除率、症状消失率及不良反应情况。结果治疗4周后,A组总有效率为91.3%高于B组的76.1%,差异有统计学意义(P<0.05)。A组症状消失率为89.1%高于B组的71.7%,差异有统计学意义(P<0.05)。且不良反应均为一过性。结论药物治疗胃溃疡时应首选埃索美拉唑联合克拉霉素和阿莫西林治疗的方案,可提高临床疗效。
作者 陆明荣
出处 《临床合理用药杂志》 2011年第13期76-77,共2页 Chinese Journal of Clinical Rational Drug Use
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