摘要
多数人认为慢性疲劳综合征 (ChronicFatigueSyndrome ,CFS)的发生可能是病毒感染、应激等多因素导致神经—内分泌—免疫网络紊乱的结果。我们根据中医理论及前期临床实践 ,认为肝脾功能失调是慢性疲劳综合征发生的机理之一。采用慢性束缚及冷水游泳加进食时电刺激的复合应激方法研制了慢性疲劳动物模型 ,并经行为学测定 ,结果与慢性疲劳综合征的临床表现基本相似。认为进一步的临床研究应以中医理论为指导 ,结合临床流行病学 /DME方法、现代多元统计学方法、国际公认的统计软件SPSS或SAS软件及一些量表的运用 ,从中西医两个角度探讨其病因病机 ,分析我国CFS的症状学特点及辨证分型 ,分析中药治疗CFS的机理 ,并对CFS病人定期随访观察 ,研究其发展、转归及预后规律 ,为制订符合我国国情的中西医结合的CFS诊断标准、确立综合临床治疗方案 ,寻找有效的预防、治疗措施提供依据。
Chronic fatigue syndrome (CFS) are most thought as the result of disturbance of neuro endocrine immune net by multi factors like the virus infection, stress, etc. Based on the TCM theory combined with earlier stage clinical practice, we thought the dysfunction of liver and spleen be one of the mechanism. The CFS animal model was established by multiple stress factors as chronic enchaining, cold swimming and electric stimulus when taking food. The praxiologic assay showed the results conformed to the clinical symptoms of CFS. Further clinical study would be under the TCM theory, using clinical epidemiology/DME method, multiple statistic method, internationally accepted statistic software SPSS or SAS, and measuring scales, discuss on the pathological mechanism from both angles of Chinese and western medicine, analyze the semiological characteristic and differentiation of syndromes and typing of CFS in China.
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
1999年第5期19-23,共5页
Journal of Beijing University of Traditional Chinese Medicine
基金
国家自然科学基金
国家中医药管理局资助
关键词
慢性疲劳综合征
病理机制
中西结合治疗
Chronic fatigue syndrome
Pathological mechanism
Chinese medicine
