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氧驱雾化吸入布地奈德联合沐舒坦治疗咳嗽变异性哮喘的临床观察 被引量:4

Oxygen atomization inhalation of budesonide and ambroxol for cough variant asthma
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摘要 目的观察氧气驱动雾化吸入布地奈德联合沐舒坦治疗咳嗽变异性哮喘的临床效果。方法将2007年1月至2009年1月在我院住院治疗的64例咳嗽变异性哮喘患儿分为观察组(34例)和对照组(30例),两组均常规控制感染、支持、对症治疗,观察组采用布地奈德联合沐舒坦氧气驱动雾化治疗,对照组采用沐舒坦氧气驱动雾化治疗加地塞米松0.5mg/(kg.d)(VD)。结果两组总有效率分别为97.06%和51.00%,差异有统计学意义(P<0.01);两组治愈率比较差异有统计学意义(P<0.01);观察组在咳嗽、喘息、气促、肺部喘鸣音消失时间及平均住院天数较对照组短,差异有统计学意义(P<0.01)。结论布地奈德联合沐舒坦氧驱雾化治疗咳嗽变异性哮喘疗效显著优于单纯沐舒坦氧驱雾化治疗,此法操作简便,缩短病程,未见明显不良反应。 Objective To study the efficacy of oxygen atomization inhalation of budesonide and ambroxol for cough variant asthma.Methods 64 patients with child cough variant asthma were randomized to treatment group(34 cases) and control group(30 cases),both groups were given infection control,supporting and symptomatic therapy.The treatment group was given oxygen atomization inhalation of budesonide and ambroxol,and control group received oxygen atomization inhalation of ambroxol.Results The response rates in the treatment group and control group were 97.06% and 93.33%,with no significant difference,but the cure rates were statistically significant(P0.01).The time of cough,asthmatic,dyspnea,lung rale and average hospitalization days in treatment group were shorter than those in control group(P0.01).Conclusion Oxygen atomization inhalation of budesonide and ambroxol is more effective than ambroxol in the treatment of bronchiolitis,with shorter disease course and no side effect.
出处 《海南医学》 CAS 2011年第12期74-75,共2页 Hainan Medical Journal
关键词 氧驱雾化吸入 布地奈德 咳嗽变异性哮喘 Oxygen atomization inhalation Budesonide Cough variant asthma
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