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子宫肌瘤^(18)F-FDG PET/CT显像高代谢机制的初步探讨 被引量:5

Primary Study of ^(18)F-FDG PET Uptake in Uterine Leiomyoma
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摘要 目的探讨18F-2-氟-2脱氧-D-葡萄糖(18F-FDG)正电子发射体层摄影术(PET)/CT显像上子宫肌瘤的高代谢表现及机制。资料与方法回顾性分析2007年7月至2010年8月接受PET/CT检查的受检女性(共1785例)的PET/CT图像,以18F-FDG摄取高于肝脏作为代谢增高的标准,子宫出现高代谢病灶者共147例,其中9例经病理证实为子宫肌瘤。结果 9例子宫肌瘤表现为18F-FDG代谢增高的受检者年龄34~57岁,平均46岁,子宫肌瘤18F-FDG代谢的18F-FDF最大标准摄取值(SUVmax)为4.4~20.4。绝经前期子宫肌瘤的18F-FDG摄取多见,且SUVmax高于绝经后期。绝经前期子宫肌瘤的18F-FDG摄取与月经周期无明显相关,但增殖期子宫肌瘤的SUVmax低于分泌期。结论子宫肌瘤可以表现为18F-FDG代谢增高,不应一概视为恶性。认识子宫肌瘤的高代谢表现有助于减少假阳性,提高诊断准确性。 Objective To investigate the 18F-FDG uptake in uterine leiomyoma on PET/CT.Materials and Meth-ods A total of 1785 females examined by whole-body 18F-FDG PET/CT were retrospectively studied.Increased 18F-FDG uptake was defined as 18F-FDG uptake greater than liver uptake.Nine cases were confirmed uterine leiomyoma by pathology.Results The 9 patients with uterine leiomyoma showed increased 18F-FDG uptake.The SUVmax of 18F-FDG in uterine leiomyoma were 4.4 to 20.4.18F-FDG uptake of uterine leiomyoma is more common in premenopausal women than in postmenopausal women.There is no significant correlation between the 18F-FDG uptake in the uterine leiomyomas and menstrual cycle,but 18F-FDG uptake during the proliferative phase was lower than that during secretory phase.Conclu-sion Increased 18F-FDG uptake is often observed in uterine leiomyoma and should not be confused with malignant accumulation.Recognize the phenomenon is helpful to improve the diagnostic accuracy.
出处 《临床放射学杂志》 CSCD 北大核心 2011年第6期852-854,共3页 Journal of Clinical Radiology
关键词 子宫肌瘤 18F-2-氟-2脱氧-D-葡萄糖 Uterine leiomyoma 18F-fluorodeoxyglucose
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参考文献9

  • 1吴建伟,艾书跃,袁梅.子宫肌瘤^(18)F-FDG高摄取1例[J].临床肿瘤学杂志,2009,14(2):191-192. 被引量:2
  • 2陈萍,邓怀福,蔡欣,陈仰纯.子宫肌瘤^(18)F-FDG PET/CT显像高代谢二例[J].中华核医学杂志,2006,26(4):250-250. 被引量:6
  • 3Sadahiko Nishizawa,Masayuki Inubushi,Aki Kido,Masao Miyagawa,Takeshi Inoue,Katsura Shinohara,Makoto Kajihara.Incidence and characteristics of uterine leiomyomas with FDG uptake[J]. Annals of Nuclear Medicine . 2008 (9)
  • 4Kazuhiro Kitajima,Koji Murakami,Erena Yamasaki,Yasushi Kaji,Kazuro Sugimura.Standardized uptake values of uterine leiomyoma with 18F-FDG PET/CT: variation with age, size, degeneration, and contrast enhancement on MRI[J]. Annals of Nuclear Medicine . 2008 (6)
  • 5Tsukada H,Murakami M,Shida Met al.18F-Fluotodeoxyglucose up-take in uterine leiomyomas in healthy women. Clinical Imaging . 2009
  • 6Yoshida Y,Tsujikawa T,Kurokawa Tet al.Assessment of fluorode-oxyglucose uptake by leiomyomas in relation to histopathologic sub-type and the menstrual state. J Compet Assist Tomogr . 2009
  • 7Wen-Ling Lee M.D. Ren-Shyan Liu M.D. Chiou-Chung Yuan M.D. Hsiang-Tai Chao M.D.,Ph.D. and Peng-Hui Wang M.D.Relationship between gonadotropin-releasing hormone agonist and myoma cellular activity: preliminary findings on positron emission tomography. Fertility and Sterility . 2001
  • 8Chura,JC,Truskinovsky,AM,Judson,PL,Johnson,L,Geller,MA,Jr,Downs,LS.Positron emission tomography and leiomyomas: clinicopathologic analysis of 3 cases of PET scan-positive leiomyomas and literature review. Gynecologic Oncology . 2007
  • 9C.Y. Lin,H.J. Ding,Y.K. Chen,C.S. Liu,C.C. Lin,C.H. Kao.F-18 FDG PET in detecting uterine leiomyoma. Clinical Imaging . 2008

二级参考文献10

  • 1李亚军,高硕,白人驹.子宫平滑肌肉瘤一例[J].中华放射学杂志,2004,38(12):1342-1343. 被引量:3
  • 2陈萍,邓怀福,蔡欣,陈仰纯.子宫肌瘤^(18)F-FDG PET/CT显像高代谢二例[J].中华核医学杂志,2006,26(4):250-250. 被引量:6
  • 3朱朝晖,程午樱,程欣,党永红.正电子发射断层显像中子宫和卵巢生理性摄取的特点[J].中国医学科学院学报,2007,29(1):124-129. 被引量:3
  • 4Lerman H,Metser U,Grisaru D, et ai. Normal and abnormal ^18F- FDG endometrial and ovarian uptake in pre-and postmenopausal patients : assessment by PET/CT[ J ]. J Nucl Med, 2004,45:266 -271.
  • 5Nishizawa S,Inubushi M,Okada H. Physiogieal 18F-FDG uptake in the ovaries and uterus of healthy female voluntees [ J]. Eur J Nucl Med Mol Imaging,2005,32:549 -556.
  • 6Kitajima K, Murakami K, Yamasaki E, et al. Standardized uptake values of uterine leiomyoma with 18F-FDG PET/CT: variation with age, size, degeneration, and contrast enhancement on MRI[J]. Ann Nucl Med. 2008, 22(6) :505 -512.
  • 7Lin CY, Ding HJ, Chen YK,et al. F-18 FDG PET in detecting uterine leiomyoma[J]. Clin Imaging, 2008, 32( 1 ) :38 -41.
  • 8Shida M, Murakami M, Tsukada H, et al. F-18 fluorodeoxyglucose uptake in leiomyomatous uterus [J ]. Int J Gynecol Cancer, 2007,17( 1 ) :285 -290.
  • 9Zor E, Stokkel MP, Ozalp S,el al. FI8-FDG coincidence-PET in patients with suspected gynecological malignancy [ J ]. Acta Radiol, 2006,47(6) :612 -617.
  • 10赖寿伟,杨华岳,邱小琴.动态增强CT扫描对子宫肌瘤的诊断价值[J].中国临床医学影像杂志,1999,10(4):264-266. 被引量:19

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