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腹腔镜术后辅助应用孕三烯酮和散结镇痛胶囊治疗卵巢子宫内膜异位囊肿疗效观察 被引量:10

The study on the efficacy of gestrinone and Sanjie zhentong capsule for the adjunctive treatment of ovarian endometriosis cyst after laparoscopic opteration
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摘要 目的 研究腹腔镜手术后辅助联合应用孕三烯酮和散结镇痛胶囊治疗卵巢子宫内膜异位囊肿的疗效.方法 将116例腹腔镜下卵巢子宫内膜异位囊肿手术后患者随机分三组:A组(孕三烯酮和散结镇痛胶囊组)42例,术后口服孕三烯酮2.5 mg/次,2次/周,连续3~6个月,散结镇痛胶囊4粒,3次/d,连续3个月.B组(孕三烯酮组)38例,术后口服孕三烯酮2.5 mg/次,2次/周,连续3~6个月.C组(散结镇痛胶囊组)36例,术后口服散结镇痛胶囊4粒,3次/d,连续3个月.所有患者随访6~12个月.结果 随访率为96.55%(112/116).A组、B组、C组临床痊愈及显效率分别为97.5%、67.6%、65.7%,总有效率分别为100.0%、94.6%、91.4%,复发率分别为2.5%、24.3%、22.9%,A组与B组,C组间差异均有统计学意义(均P<0.05).三组副反应发生率分别为35.0%、29.7%、14.3%,差异无统计学意义(P>0.05).结论 孕三烯酮联合散结镇痛胶囊用于卵巢子宫内膜异位囊肿腹腔镜术后辅助治疗的疗效好于单一用药. Objective To study the efficacy of gestrinone and Sanjie zhentong capsule for the adjunctive treatment of endometriesis cyst of ovary after laparoscopic operation.Methods 116 patients with ovarian endometriosis cyst after laparoscopic operation were randomly divided into three groups:A group(gestfinone and Sanjie Zhentong capsule,n=42),after operation were given gestrinone(2.5mg each time,two times per-week for 3~months)and Sanjie zhentong capsule(4 pills each time,three times everyday for 3 months);B group(gestrinone,n=38),after operation were only given gestrinone(2.5mg each time,two times per-week for 3-6 months);C group(Sanjie zhentong capsules,n=36),after operation were only given Sanjie zhentong capsules(4 pills each time,three times everyday for 3 months).All patients were followed up for 6~12 months.Results The follow-up visit rate was 96.5%(112/116).A group,B group and C group,their excellence rate was respectively 97.5%,67.6%and 65.7%,their recurrence rate was respectively 2.5%,24.3%and 22.9%.There was significant difference between A group and B group.C group(P<0.05).Incidence rate of three groups'side effects was respectively 35.0%,29.7%and 14.3%,there was no significant difference among three groups(P>0.05).Conclusion The efficacy of gestfinone and Sanjie zhentong capsule for the adjunctive treatment of endometriosis cyst of ovary after laparoscopic operation was better than that of the only medicine treatment.
出处 《中国基层医药》 CAS 2011年第10期1331-1332,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 子宫内膜异位症 卵巢囊肿 孕三烯酮 腹腔镜手术 Endometriosis Ovarian cyst Gestrinone Laparoscopic operation
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