摘要
随着基础医学与临床医学脱节现象的日益凸显,作为二者之间连接纽带和桥梁的转化医学越来越受到重视。近年来,转化医学在美、欧等西方国家迅速发展,在我国也正成为"十二五"期间医学领域的重要发展方向之一。分子影像作为现代分子生物学与先进医学影像技术相结合的产物,可以利用影像方法对活体内分子的生物化学过程进行定性和定量研究,是将基础医学研究成果迅速向临床应用转化的重要工具和主要路径,可在疾病的发生、发展和转归研究中,在药物的研制、开发和评价中,以及在诊断和治疗新技术的转化应用中,发挥重要的作用。
The gap between basic medical research and clinical application becomes more and more prominent,and translational medicine emerges as a bridge between them.Recently,translational medicine is undergoing an incredible growth in the developed countries,especially in Europe and United States of America.In China,translational medicine is considered as one of the main topics in the national ＂12th Five-Year Plan＂.Meanwhile,being the hybrid of modern molecular biology and advanced medical imaging technology,molecular imaging holds the ability of both qualitative and quantitative investigation of biochemistry changes in vivo,and it＇s an important tool that can directly translate preclinical research outcomes into clinical use.Molecular imaging is playing an increasing significant role not only in the research of disease etiopathology,progression,and turnover,but also in new drug research,development,and evaluation,as well as in the translation of new technologies for molecular diagnosis and treatment.Therefore,molecular imaging is acting as an important route of translational medicine.
出处
《生物物理学报》
CAS
CSCD
北大核心
2011年第4期327-334,共8页
Acta Biophysica Sinica
基金
国家自然科学基金项目(30870725
81071189)~~
关键词
分子影像
转化医学
基础医学研究
临床应用
Molecular imaging
Translational medicine
Basic medical research
Clinical application
