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结节性甲状腺肿术后部分抑制疗法的临床观察 被引量:4

Clinical observation on postoperative partial inhibition therapy for nodular goiter
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摘要 目的研究结节性甲状腺肿(NG)术后服用左旋甲状腺素(L-T4)进行部分抑制疗法在预防复发中的作用。方法结节性甲状腺肿术后分为服药组(口服L-T4)和对照组,使用B超、CT等检查手段随访3~6年,分析口服L-T4进行部分抑制疗法与术后复发的关系。结果术后随访302例,发现甲状腺结节复发24例,复发率为7.95%。其中服药组206人,复发6人,复发率为2.91%;对照组96人,复发18人,复发率为18.75%,二者有统计学意义(P〈0.05)。结论结节性甲状腺肿术后可给予口服L-T4进行部分抑制疗法能降低复发率。 Objective To study the effect of adopting partial inhibition therapy by administrating levothyroxine(levothyroxine,L-T4) on the prevention of recurrence after surgery for nodular goiter(NG).Methods Patients who underwent surgeries for NG were divvied into administration group(oral administration of L-T4) and control group.The follow-up went for 3~6 years by means of B-utralsound,CT and other examinations.The relationship between the partial inhibition therapy by oral administration of L-T4 and the postoperative recurrence was analyzed.Results Totally 302 patients(206 in administration group and 96 in control group) received the follow-up and recurrences were found in 24 patients(6 in administration group and 18 in control group),the recurrence rates was 7.95%(2.91%in administration group and 15.63% in control group).Statistic significances were found between the two groups(P0.05).Conclusion Partial inhibition therapy by oral administration of L-T4 can reduce the recurrence rate after surgery for NG.
作者 沈锋
出处 《局解手术学杂志》 2011年第3期272-273,共2页 Journal of Regional Anatomy and Operative Surgery
关键词 结节性甲状腺肿 外科治疗 左旋甲状腺素 复发 nodular goiter surgical treatment levothyroxine recurrence
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