摘要
目的探讨海口地区过敏性鼻炎并哮喘患儿过敏原分布情况及与临床的关系。方法采用德国Allergopharma公司提供的国际标准化过敏原试剂14种,运用皮肤点刺试验,对2007-01至2009-09收治的224例过敏性鼻炎并发哮喘患儿进行检测。结果 224例中过敏原皮试阳性169例,其中男90例,女79例,平均年龄(8.67±1.81)岁,3～6岁112例,7～12岁57例;春季发病11例,夏季发病19例,秋季发病80例,冬季发病59例;被过敏原致敏者中以螨虫及虾过敏原居多,大多同时被两种过敏原致敏,患儿大部分合并霉菌过敏原阳性反应;过敏原阳性率学龄前患儿高于学龄期患儿,且与季节有明显相关性,以秋冬季更为显著。结论 海口地区过敏性鼻炎并哮喘患儿中,75.50%患儿过敏原皮试呈阳性反应,且同时有两种过敏原阳性;过敏原阳性与季节、年龄有关。
Objective To study the distribution of allergens and its clinical characteristics among children with allergic rhinitis complicated by bronchial asthma in Haikou Area. Methods 224 children with allergic rhinitis complicated by bronchial asthma were tested with 14 kinds of international standardized allergens by skin prick test . These allergens were provided by Allergopharma Company in Germany. Results 169 of the 224 children had positive skin test results （90 males and 79 females, mean age = 8.67 ±1.81 years）. 112 children were 3 - 6 years old and 57 were 7 - 12 years old. 11 children began presenting symptoms in spring, 19 in summer, 80 in autumn and 59 in winter. Most of the children with positive results were sensitive to mites and shrimps. They were particularly sensitive to moulds at the same time. The positive rate was higher in preschool children than in school -age children, depending on the season. Conclusions 75.50% of the children with allergic rhinitis complicated by bronchial asthma in Haikou Area have positive results in allergen skin tests. The positive rate is associated with the season and age. The main allergens are shrimps, mites and moulds. Most of the children with positive results are sensitive to two kinds of allergens at the same time.
出处
《武警医学》
CAS
2011年第5期401-403,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
过敏原
过敏性鼻炎
哮喘
分布
allergens
allergic rhinitis
bronchial asthma
distribution
