摘要
目的探讨北京地区人群血清多种维生素含量与变应性鼻炎的相关性。方法随机选取2017年11月-2018年12月就诊于解放军总医院第一医学中心耳鼻咽喉头颈外科医学部的北京地区变应性鼻炎患者214例(变应性鼻炎组)和健康查体志愿者41例(对照组),抽血后进行维生素A、维生素B1、维生素B2、维生素B6、维生素B9、维生素B12、维生素C、维生素D、维生素E的检测。结果变应性鼻炎组患者血液样本的维生素B6[Md(IQR):38.88(35.54,40.52)nmol/L vs 37.01(27.56,39.57)nmol/L]、维生素B12[Md(IQR):504.83(443.43,574.64)pg/ml vs 464.58(411.81,533.32)pg/ml]和维生素D[Md(IQR):49.50(40.52,61.30)nmol/L vs 43.50(36.08,50.85)nmol/L]的含量总体高于对照组,差异均有统计学意义(P<0.05),三种维生素的中位数均在正常范围内。两组维生素A、维生素B1、维生素B2、维生素B9、维生素C和维生素E含量的差异均无统计学意义(P>0.05)。结论变应性鼻炎患者血液中的维生素B6、维生素B12及维生素D含量高于对照组,但是否与变应性鼻炎相关,还需进一步研究。
Objective To observe the correlation between vitamins levels and allergic rhinitis.Methods From November 2017 to December 2018,214 allergic rhinitis patients admitted to our hospital and another 41 healthy controls who had undergone physical examination were enrolled.The levels of vitamin A,B1,B2,B6,B9,B12,C,D and E were detected.Results The levels of vitamin B6(Md[IQR]:38.88[35.54,40.52]nmol/L vs 37.01[27.56,39.57]nmol/L),B12(Md[IQR]:504.83[443.43,574.64]pg/ml vs 464.58[411.81,533.32]pg/ml)and vitamin D(Md[IQR]:49.50[40.52,61.30]nmol/L vs 43.50[36.08,50.85]nmol/L)in the allergic rhinitis group were higher than those in the normal control group with statistically significant differences(all P<0.05).The levels of vitamins in the two groups were all in the normal range.There was no significant difference in levels of vitamin A,B1,B2,B9,C and E between the two groups(P>0.05).Conclusion The results show that the levels of vitamin B6,B12 and D are higher in the allergic rhinitis group than those in the normal control group.However,further study is needed to explore the relationship between vitamin and allergic rhinitis.
作者
刘日渊
王荣光
杨仕明
LIU Riyuan;WANG Rongguang;YANG Shiming(College of Otolaryngology Head and Neck Surgery,China National Clinical Research Center for Otolaryngologic Diseases,Key Lab of Hearing Impairment Science of Ministry of Education,Key Lab of Hearing Impairment Prevention and Treatment of Beijing the First Medical Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《解放军医学院学报》
CAS
2020年第7期712-714,742,共4页
Academic Journal of Chinese PLA Medical School
