摘要
阿霉素作为临床常用的蒽环类恶性肿瘤药物,其心脏毒性、骨髓抑制及消化道不良反应限制了临床应用。自从脂质体被发现,并作为抗肿瘤药物的有效载体后,取得了良好的抗肿瘤效果,并降低毒副作用。文章对阿霉素脂质体的应用优势和研究进展进行综述。
As a common clinical cancer drugs anthracycline doxorubicin,its cardiac toxicity,bone marrow suppression and gastrointestinal side effects limit its clinical application.Since the liposomes were found as an effective carrier of anticancer drugs,a good antitumor effect and reduced side effects were obtained.Application advantages and research progress of liposomal doxorubicin were reviewed.
出处
《中国肿瘤》
CAS
2011年第5期372-377,共6页
China Cancer
关键词
阿霉素
脂质体
靶向治疗
肿瘤
doxorubicin
liposomes
targeting therapy
neoplasms
