摘要
目的:探讨孕早期不同类型心理社会应激与先天性心脏病的关系,为先天性心脏病的预防提供依据。方法:使用自编调查问卷,对86例先天性心脏病患儿和按照1∶2原则匹配性别、年龄、出生地选择的172例正常对照儿童的母亲分别进行面对面问卷调查。使用SPSS 10.0统计学软件进行统计分析。结果:孕早期总负性心理社会应激性生活事件数量在文化程度低的孕妇中高于文化程度较高的孕妇,差异具有统计学意义(P<0.05)。先天性心脏病主要为房间隔缺损(41.9%)和室间隔缺损(33.7%)。孕早期急性负性心理社会应激性生活事件数量先天性心脏病组高于对照组,差异具有统计学意义(P<0.05)。结论:孕早期急性负性心理社会应激可能对子代先天性心脏病的发病影响更大,文化程度较低的孕妇群体更加应该引起关注。
Objective：To explore the relationship between psychosocial stress and congenital heart disease during early pregnancy,so as to provide scientific evidence for congenital heart disease prevention.Methods：A 1∶2 matched case-control study was designed.86 mothers with congenital heart disease children,and 172 mothers with normal children which matching with congenital heart disease children by sex,age and birth area were recruited in this study.All mothers were interviewed with a questionnaire by the child health care doctors.Results：In early pregnancy,the number of total negative psychosocial life events among the pregnant women having low education level was significantly higher than the pregnant women with high education level（P0.05）.The primary types of congenital heart disease were atrial septal defect（41.9%） and ventricular septal defect（33.7%）.The number of acute negative psychosocial life events in early pregnancy was significantly higher than that of control group（P0.05）.Conclusion：The acute negative psychosocial life events in early pregnancy may effect on the congenital heart disease of offspring.We should pay attention to pregnant women who with low level of education.
出处
《中国妇幼保健》
CAS
北大核心
2011年第14期2153-2155,共3页
Maternal and Child Health Care of China
基金
马鞍山市卫生局第七批科教专项资金资助课题(2007-13)
