摘要
患者男,71岁。反复午后发热1个月,胸腔积液收入呼吸科。入院后查抗结核抗体:弱阳性;ANA(+);血常规示贫血及白细胞减少。以结核性胸膜炎予抗结核治疗3周无明显好转,短期使用糖皮质激素后病情缓解。患者继续抗结核治疗4月后皮疹加重。查ANA1:3200(+),Histone抗体(+);dsDNA-IgG194.8IU/mL,结合患者关节炎、皮疹、胸膜炎及贫血等病史,诊断:系统性红斑狼疮。予口服强的松15mg1次/d,羟氯喹100mg2次/d,症状缓解,随访半年病情稳定。
A 71-year-old male patient was adimitted to the hospital because of recurrent fever in the afternoon for a month and pleural effusion. Test showed ＂Anti-Lipoarabinomannan Antiboby （ ＋ ） ;ANA （ ＋ ） ;WBC 2.3 × 10^9/L, Hb 99g/L＂. The patient was diagnosed tuberculosis pleuritis and given Isoniazid and Ethambutol for 3 weeks. However there was no obvious relief of symptoms. Then glucocorticoids was used, and the patient got better immediately. The patient continued to take antituberculosis medicines in the next 4 months. Immunologic examination showed ： ＂ANA 1：3200（ ＋ ）, histone（ ＋ ） ;dsDNA-IgG 194.8IU/mL＂. Considering all the clinical symptoms, the patient was diagnosed as Systemic Lupus Erythematosus （SLE）. The patient reciered Prednisone, 15mg once daily and hydroxychloroquine 100mg, twice daily . During a follow-up of 6 months, all symptoms disappeared without recurrence.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2011年第5期399-400,共2页
The Chinese Journal of Dermatovenereology
