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大鼠大脑中动脉缺血后环氧合酶-2表达的研究

Expression of cyclooxygenase 2 following ischemic middle cerebral artery in rat
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摘要 目的 研究大鼠大脑中动脉缺血后环氧合酶-2(cyclooxygenase-2,COX-2)的表达。方法 采用栓线法制备大脑中动脉缺血模型,利用免疫组化方法检测COX-2 表达情况。结果 脑缺血区的周围大脑皮质及远隔的海马回区域有COX-2 蛋白质表达。结论 在COX-2 Objective Made ischemic models of middle cerebral artery in rat and expression of cyclooxygenase 2. Methods Thread technique was used to make ischemic models of middle cerebral artery and measure expression of cyclooxygenase 2 by immun ohistochemistry. Result There was expression of cyclooxygenase 2 in surroundings cortex of cerebral ischemia and remote hippocampus. Conclusion accelerae metabolism of arachidonic acid can be in these regions.
出处 《中风与神经疾病杂志》 CAS CSCD 北大核心 1999年第5期275-276,共2页 Journal of Apoplexy and Nervous Diseases
关键词 环氧合酶-2 花生四烯酸 局灶性 脑缺血 大鼠 Cyclooxygenase 2 Arachidonic acid Focal cerebral ischemia Immunohistochemistrysion:The interventional treatment is a safer and effective method for advanced or recurrent intrapelvic malignancy tumors. Key words Pelvic malignancy tumor I
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