摘要
目的:分析35例唾液腺腺样囊性癌(salivary adenoid cysti ccarcinoma,SACC)患者的发病情况,探讨影响SACC的预后因素。方法:收集1983—2008年在安徽医科大学附属安庆医院口腔颌面外科手术治疗经病理科确诊为唾液腺SACC的患者35例,按照UICC(2002年)TNM分类方法,时其进行临床分期,按照WHO(2005年)唾液腺肿瘤组织学分类法进行病理分类。结果:SACC多发于腮腺和下颌下腺,平均患病年龄43.8岁,男女比为1.5:1;SACC的死亡原因主要是局部复发和远处转移,发生在下颌下腺和腭部及其他小唾液腺的SACC复发率和转移率较发生于腮腺的高,临床Ⅲ和Ⅳ期相对于I和Ⅱ期的复发率高,实性型比腺样一管状型SACC的复发率和转移率高,神经侵犯者比非神经侵犯者SACC的复发率和转移率高。结论:SACC是较为常见的唾液腺恶性肿瘤;SACC术后复发率和转移率较高,这与肿瘤的发病部位、临床分期、病理分型及有无神经侵袭情况具有相关性。
Objective: This was to analyze the clinical manifestation of salivary adenoid cystic carcinoma(SACC) in 35 patients, and studied the important factors related to the prognosis comprehensively. Methods: Collect with 35esscs of SACC. The clinical stage was carried out by the TNM classification of UICC in 2002, and by the pathologic type according to the new method of WHO in 2005 ( salivary 2005. nd tumor). Results :Adenoid cystic carcinoma was most common in salivary gland malig- nant tumors. Parotid gland and submandibular gland were the most commonly original sites. The age of patients was 43.8 in average with the ratio of male to female being 1.5:1. The main cause of death in SACC was local currence and distant metastasis. The rates of recurrence and metastasis were higher in submandibular gland and minor salivary Stand in palate, Ⅲ and Ⅳ stage, solid type and nerve invaded than other sites, Ⅰ and Ⅱ stage, sieve--tubular and non--nerve invaded. Conclusion: Salivary adenoid cystic carcinoma is the most common salivary malignant tumor with high morbidity. The recurrence and metastasis rates in SACC are hish after treatment,which depend upon sites of tumor, clinical stage ,histological type and nerve involvement.
出处
《医学信息(中旬刊)》
2011年第5期1694-1695,共2页
Medical Information Operations Sciences Fascicule
关键词
唾液腺肿瘤
腺样囊性癌
复发
转移
Salivary gland tumor
Adenoid cystic Carcinoma
Recurrence
Metastasis