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早产儿雌激素水平的检测及临床生理学意义的探讨

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摘要 目的通过检测早产儿生后体内雌二醇水平的变化趋势,探讨雌激素对早产儿的临床生理学意义。方法检测30例早产儿、30例足月儿脐带血和产妇血清及生后24h、48h新生儿血清中雌二醇含量进行分析比较,同时对28例孕早期妇女血清中的雌二醇含量进行了检测分析。结果①早产儿、足月儿脐血中雌二醇浓度与产妇血中雌二醇浓度相同,早产儿、足月儿生后24h雌二醇浓度明显下降,生后48h全部降至正常;②母体在孕期5周左右血液中雌二醇浓度明显上升,至12周左右可升至3600pg/mL并持续至足月分娩。结论应重视早产儿提前出生所伴随的雌激素缺失状态。
作者 郝日成
机构地区 山西省大同县人民医院儿科
出处 《中国医药指南》 2011年第13期275-276,共2页 Guide of China Medicine
关键词 早产儿 雌激素 缺失状态 生理学意义
分类号 R722 [医药卫生—儿科]
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参考文献4

  • 1Brarnnvall K,Korhonen L,LindholM D.Estrogen-receptor-dependent regulation of neural stem cell proliferetion and differentiation[J].Mol Cell Neurosci,2002,21(3):512.
  • 2Noeoury R,Cutter WJ,Compton J,et al.The neumpropeflive effects of estrogen on the aging brain[J].Exp Gerontol,2003,38(12):109-117.
  • 3Cheame ZF,Santillano DR,Wade SB,et al.The extra-cellular matrix,P53 and estrogen compete to regulate cell-surface Fas/ Ape-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors,and reciprocally,Fas-ligand modifies estrogen control of cell cycle protein[J].J Neurosci,2004,35(1):11.
  • 4李晓莉,高钰琪.雌激素对缺氧保护作用的研究进展[J].中国药理学通报,2003,19(2):134-137. 被引量：4

二级参考文献20

  • 1[3]Griffin M, Lee HW, Zhao L et al. Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia:effects of estrogen. Mol Cell Biochem, 2000;215(1～2):21～30
  • 2[5]Kim YD, Chen B, Beauregard J et al. 17 β-Estradiol prevents dysfunction of canine coronary endotheleum and myocardium and reperfusion arrhythmias after brief ischemia/reperfusion. Circulation,1996;94(11):2091～8
  • 3[6]Razandi M, Pedram A, Levin ER. Estrogen signals to the preservation of endothelial cell form and function. J Biol Chem, 2000;275(49):38540～6
  • 4[7]Ruohola JK, Valve EM, Karkkainen MJ et al. Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells. Mol Cell Endocrinol, 1999;149(1～2):29～40
  • 5[8]Classen LI, Alfer J, Kresche CA et al. Progestins, progesterone receptor modulators, and progesterone antagonists change VEGF release of endometrial cells in culture. Steroids, 2000;65(10～11),763～71
  • 6[9]Bausero P, Ben Mahdi M,Mazucatelli J et al. Vascular endothelial growth factor is modulated in vascular muscle cells by estradiol, tamoxifen, and hypoxia. Am J Physiol Heart Circ Physiol, 2000;279(5):H2033～42
  • 7[11]Jovanovic S, Jovanovic A, Shen W. Low concentrations of 17 beta-estradiol protect single cardiac cells against metabolic stress-induced Ca2+ loading. J Am Coll Cardiol, 2000;36(3):948～52
  • 8[13]Uchiyama T, Kurabayashi M, Ohyama Y et al. Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through ginistein-sensitive tyrosine kinase pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol, 2000;20(4):1155～6
  • 9[14]Greene RA. Estrogen and cerebral blood flow: A mechanism to explain the impact of estrogen on the incidence and treatment of Alzheimer's disease. Int J Fertil Womens Med, 2000;45(4):253～7
  • 10[15]Zaulyanov LL,Green PS, Simpkins JW. Gltamate receptor requirement for neuronal death from anoxia-reoxygenation: An in Vitro model for assessment of the neuroprotective effects of estrogens. Cell Mol Neurobiol, 1999;19(6):705～18

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中国医药指南
2011年 第13期

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