摘要
目的探讨高血压患者的血液流变学与血小板参数的变化及其临床意义。方法检测78例高血压患者及72例健康对照组血液流变学各项指标，分析比较其差异。结果Ⅰ期高血压患者各种血液流变学及血小板参数指标与健康对照组差异无统计学意义（P〉0．05）；Ⅱ期和Ⅲ期高血压患者各种血液流变学指标较Ⅰ期和对照组均显著升高，差异均有统计学意义[t值分别为（16．659、7．104、8．474、10．151、6．653）和（18．697、7．479、10．441、13．273、10．094、8．057），均P〈0．05]，Ⅱ期Ⅲ期高血压患者血小板参数指标较Ⅰ期和对照组也均显著升高，差异均有统计学意义[t值分别为（5．745、4．921、6．527、24．72）和（8．224、6．982、5．636、22．676），均P〈0．05]；Ⅲ期高血压患者各种血液流变学指标较Ⅱ期均显著升高，差异均有统计学意义（t=5．655、5．714、5．126、12．153、7．144、6．722，均P〈0．05）；Ⅲ期高血压患者血小板参数较Ⅱ期也均显著升高，差异均有统计学意义（t=5．182、6．780、3．917、8．969，均P〈0．05）。结论血液流变学指标及血小板参数的改变与高血压发生密切相关，有助于高血压患者的临床诊断，对高血压的治疗、监测、预后有着重要的意义。
Objective To investigate the changes and clinical significance of hemorrheology and platelet parameters examination in patients with hypertension. Methods Hemorrheology and platelet parameters were detected in 78 patients with hypertension and in 72 healthy subjects as control group. Then difference were compared. Results The hemorrheology and platelet parameters in he patients with hypertension at stage I were no different in comparison with the control group（ all P 〉 0.05） , which at stage Ⅱ and Ⅲ were significantly different in comparison with stage I and the control group （ all P 〈 0.05 ）. and at stage Ⅲ were significantly different in comparison with stage Ⅱ （ all P 〈 0.0 5 ） . Conclusion The changes ofhemorheology and platelet parameters were closely related with hypertension, which were helpful to the clinical diagnosis of hypertension and had important significance to the therapy ,monitor and prognosis of hypertension.
出处
《中国基层医药》
CAS
2011年第6期773-775,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
高血压
血液流变学
血小板
Hypertension
Hemorheology
Blood platelets
