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蔗糖铁联合促红细胞生成素治疗血液透析患者肾性贫血的疗效观察 被引量:6

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摘要 目的观察蔗糖铁联合促红细胞生成素(EPO)治疗血液透析患者肾性贫血的临床效果,探讨血液透析患者肾性贫血的最佳治疗方案。方法选择血液透析伴肾性贫血患者136例,随机分为对照组与观察组,各68例。对照组采用EPO治疗,观察组患者采用蔗糖铁联合EPO治疗。治疗8周后观察2组临床疗效和血红蛋白(Hb)、红细胞(RBC)、红细胞压积(HCT)、血清铁蛋白(SF)及血清转铁蛋白饱和度(TSAT)水平。结果治疗8周后,观察组总有效率为86.8%高于对照组的72.1%,差异有统计学意义(P<0.05)。治疗8周后,观察组Hb、RBC、HCT、SF及TSAT水平均优于对照组,差异有统计学意义(P<0.05)。结论治疗血液透析患者肾性贫血时,首选蔗糖铁联合EPO治疗,可有效为善贫血症状、提高临床疗效。
出处 《临床合理用药杂志》 2011年第7期62-63,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1陈香美,孙雪峰,蔡广研.重组人促红细胞生成素在肾性贫血中合理应用的专家共识[J].中国血液净化,2007,6(8):440-443. 被引量:112
  • 2王海燕.肾脏病学[M] 2版[M].北京:人民卫生出版社,1998.1034.
  • 3Lopez-Gomez JM, Portoles JM, Aljama P. Factors that condition the re- sponse to erythropoietin in patients on hemodialysis and their relation to mortality[J]. Kidney Int Supp1,2008,111 : S75-81.
  • 4Fishbane S. What is needed to achieve a hemoglobin of 11-13g/dl in end-stage renal disease [ J ]. Blood Pruif,2007,25 ( 1 ) : 53 -57.
  • 5Merino A, Nogueras S, Buendia P, et al. Microinflammation and endothe- lial damage in hemodialysis [ J ]. Contrib Nephro1,2008,161 ( 2 ) : 83-88.
  • 6Owen WF,Lowrie EG. C-reactive protein as an outcome predictor for mai- ntenance hemodialysis patients[J]. Kidney Int,1998,54(2) :627-636.
  • 7Wassmann S, Stumpf M, Strehlow K, et al. Interleukin-6 induces oxida- tive stress and endothelial dysfunction by overexpression of the angiotensin Ⅱ type 1 receptor[J]. Cire Res,2004,94(4) :534-541.
  • 8Durose CL, Holdsworth M, Watson V, et al. Knowledge of dietary restric- tions and the medical consequences of noncompliance by patients on he- modialysis are not predictive of dietary compliance [ J ]. J Am Diet As- soc ,2004,104( 1 ) :35-41.
  • 9Tarng DC, Liu TY, Huang TP. Protective effect of vitamin-C on 8-hydrox- y-2, -deoxyguanosine level in peripheral blood lymphocytes of chronic he- modialysis patients[ J]. Kidney Int ,200d, ,66( 12 ) :820-831.
  • 10Yoichiro O,Tetsu W, Hiroki T, e t al.Association of renal tubu- lar damage with cardio-renal anemia syndrome in patients with heart failure[J].Int J Cardiol, 2014,173 (2) : 222-228.

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