摘要
目的：观察氨氯地平对盐敏感性高血压患者的降压作用。 对象和方法：６０ 例轻、中度高血压患者用急性静脉盐水负荷试验确定盐敏感性，于服用安慰剂两周后随机分为氨氯地平组和依那普利组，总疗程 １２ 周，于治疗前、后监测 ２４ 小时动态血压。 结果：氨氯地平对盐敏感性高血压患者的降压作用明显优于依那普利， Ｐ均＜ ０．０１。 结论：氨氯地平对盐敏性高血压的降压作用优于依那普利。
Aim:To observe the effects of amlodipine on ABPM in hypertensive patients with salt sensitivity. Design and Methods:After determination of salt sensitivity(SS) by acute salt load by Weinberger methods and use placebo as run in for two weeks, 60 mild or moderate hypertensive patients were randomly divided into amlodipine group and enalapril group. The dosage was titrated for two weeks until the targeted blood pressure(140 mmHg/90 mmHg) was achieved. Before and after treatment for 12 weeks. The ambulatory blood pressure was measured. Results:For the treatment of blood pressure in salt sensitive patients, amlodipine is superior to enalapril. Conclusion:amlodipine is superior to enalapril in the control of blood pressure in hypertensive patients with salt sensitivity.
出处
《高血压杂志》
CSCD
1999年第3期251-253,共3页
Chinese Journal of Hypertension
关键词
高血压
盐敏感性
动态血压
氨氯地平
治疗
amlodipine
Hypertension salt sensitivity
Ambulatory Blood pressure
