摘要
目的研究尿微量白蛋白(mAlb)与血清超敏C-反应蛋白(hs-CRP)联合测定对2型糖尿病(T2DM)患者早期肾损伤的诊断价值。方法对60例2型糖尿病患者及60例健康体检者的尿微量白蛋白与血清超敏C-反应蛋白,采用日立7180型生化分析仪,使用志荣公司提供的尿微量白蛋白检测试剂盒及血清超敏C-反应蛋白检测试剂盒,应用免疫比浊法进行测定,并对两种指标的相关性进行分析。结果 2型糖尿病组超C-反应蛋白为(3.58±1.06)mg/L,尿微量白蛋白为(36.54±10.27)mg/L,与健康对照组相比均差异有统计学意义(P<0.05)。结论血清超C-反应蛋白和尿微量白蛋白的联合检测,可以有效提高对2型糖尿病肾病早期的检测率。
OBJECTIVE To evaluate the diagnosis value of combined detection of mAlb and hs-CRP for early renal damage of type 2 diabetes mellitus（T2DM）.METHODS A total of 60 patients with type 2 diabetes patients and 60 healthy subjects who microalbuminuria（mAlb） and serum high sensitivity C-reactive protein（hs-CRP） were determined by using Hitachi 7180 type analyzer,using the Chi Wing offers detection of urinary albumin Kit and serum high sensitivity C-reactive protein assay kit,immuno turbidimetry were measured,and the correlation between two indicators was analyzed.RESULTS The results showed that patients with type 2 diabetes group,the super-serum C-reactive protein was 3.58±1.06mg/L and urinary albumin level was 36.54±10.27mg/L,two indicators are compared with the control group were significant differences（P0.05）.CONCLUSION By joint use of the super-serum C-reactive protein and urinary albumin level,the detection of early diabetic nephropathy in type 2 detection rate can be significantly improved.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第10期2019-2021,共3页
Chinese Journal of Nosocomiology
关键词
2型糖尿病
血清超敏
C-反应蛋白
尿微量白蛋白
Type 2 diabetes mellitus
High-sensitivity
C-reactive protein
Microalbuminuria
