摘要
与传统的荧光标志物相比,量子点由于具有荧光度强、光化学稳定性好等独特的光学性质,已被作为荧光标志用于体内外生物分子、细胞及药物作用的成像和长时间示踪等研究,显示出了巨大的发展前景。近年来人们将不同材料的纳米量子点与各种生物大分子相耦联,用于对生物大分子的功能、细胞内定位、相互作用及运动轨迹等观察研究。现就目前量子点在生物大分子中的研究概况进行总结。
Optical properties of quantum dots are advantageous against convenrtional organic fluorescent dyes,including extreme brightness,good photochemical stability,and other unique properties.Quantum dots have been used as a fluorescent marker for biological molecules both in vivo and in vitro,cells and drugs imaging,and long-time tracer studies,with a great developmental prospect.In recent years,different quantum dot materials are coupled with various biological macromolecule phases for the study of biological macromolecules function,cellular positioning,interaction,and trajectory.In this article,we summarize the implications of quantum dots in biological macromolecules.
出处
《医学综述》
2011年第7期963-966,共4页
Medical Recapitulate
关键词
量子点
生物大分子
荧光能量转移
定量检测
运动轨迹
Quantum dots
Biomacromolecule
Fluorescence energy transfer
Quantitative detection
Motion trajectory
