摘要
在对锰铁冶炼和电焊作业工人锰的累积暴露剂量评价的基础上，探讨了锰对工人的早期效应。结果发现，锰对工人神经系统功能的影响主要表现为手稳定度、反应速度、记忆力和注意力的下降，并且有随暴露剂量增加而行为功能改变严重的趋势。提示锰的累积暴露水平达１ｍｇ／ｍ＋３．年时，可能对工人神经系统产生早期亚临床改变。
The aim of this study was to assess the neurotoxic effects associated with the level of airborne manganese in the work place.A cumulative exposure index(CEI)was calculated for each subject.The neurobehavioral test battery,in terms of choosing reaction time,finger tapping,digit symbol,stylus in hole,Benton visual retention and Santa Ana dexterity was applied in the study.The manganese exposed workers had slower motor and response speed,poorer visuomotor coordination and steadiness.There was a doseresponse relationship tendency between the cumulative exposure index and the behavioral function.Hence the neurobehavioral test may be a sensitive method in detecting early changes in motor and cognitive function among manganeseexposed workers.The study also demonstrates that the cumulative exposure of manganese abuout 1mg/m3 per year may induce subclinical signs of intoxication.
出处
《卫生研究》
CAS
CSCD
北大核心
1999年第4期198-199,202,共3页
Journal of Hygiene Research
基金
中国预防医学科学院资助
