期刊文献+

肺癌化疗后病人恶心与呕吐危险因素Logistic分析 被引量:8

THE LOGISTIC REGRESSION ANALYSIS OF RISK FACTORS RELATED WITH NAUSEA AND VOMITING IN PATIENTS TREATED WITH CHEMOTHERAPY FOR LUNG CANCER
暂未订购
导出
摘要 目的探讨肺癌病人化疗后恶心、呕吐的相关危险因素。方法采用两分类Logistic回归分析,对459例接受化疗的晚期肺癌病人临床资料进行回顾性分析,统计学处理采用SPSS 11.5软件。结果恶心、呕吐相关危险因素有性别、年龄、饮酒、是否含铂制剂、铂制剂用量和化疗次数。结论在临床选择化疗方案时,应综合考虑恶心、呕吐相关危险因素,以减少病人的不良反应。 Objective To discuss the related risk factors of nausea and vomiting in patients after chemotherapy for lung cancer. Methods Logistic multivariate regression analysis was applied to make a retrospective analysis of the clinical data of 459 lung cancer patients treated with chemotherapy.SPSS 11.5 was used for the analysis. Results The risk factors related with nausea and vomiting were sex,age,alcohol drinking,with or without platiniferous preparation,the dose of platinum,and times of chemotherapy. Conclusion Some related risk factors,such as nausea and vomiting,should be considered when selecting chemotherapy in order to reduce adverse events.
出处 《齐鲁医学杂志》 2011年第3期209-210,213,共3页 Medical Journal of Qilu
基金 青岛市科技局立项课题(09KZJ-43)
关键词 恶心 呕吐 肺肿瘤 抗肿瘤联合化疗方案 危险因素 nausea vomiting lung neoplasms antineoplastic combined chemotherapy protocols risk factors
  • 相关文献

参考文献7

二级参考文献32

  • 1彭忠民,罗静,王潍博,王晓航,陈景寒,兰守敏.耐药相关基因表达对Ⅲ期非小细胞肺癌新辅助化疗的临床预测价值探讨[J].癌症,2004,23(8):963-967. 被引量:7
  • 2赵东波,陈景寒,彭忠民.Bcl-2在Ⅲ期非小细胞肺癌新辅助化疗中的临床意义[J].山东大学学报(医学版),2005,43(1):69-71. 被引量:2
  • 3高振平,宋玉良,阎明鉴,戴桂林.成人脑干中缝外区5-羟色胺细胞的分布[J].白求恩医科大学学报,1994,20(1):23-23. 被引量:4
  • 4EDELMAN M J,GANDARA D R,ROACH M3 R D,et al.Multimodality therapy in stage Ⅲ non-small cell lung cancer[J].Ann Thorac Surg,1996,61(5):1564-1572.
  • 5ROSELL,GOMEZ C J,CAMPS C,et al.Pieresectional chemotherapy in stage ⅢA non-small-cell lung cancer:a 7-year assessment of a randomized controlled trial[J].Lung Cancer,1999,26(1):7-14.
  • 6SPASOVA I,PETERA J,HYTYCH V.The role of neoadjuvant chemotherapy in marginally resectable or unresectable stage Ⅲ non-small-cell lung cancer[J].Neoplasma,2002,49(3):189-196.
  • 7SHAROUNI S Y,KAL H B,BATTERMANN J J.Accele-rated regrowth of non-small-cell lung tumours after induction chemotherapy[J].Br J Cancer,2003,89(12):2184-2189.
  • 8ALBERTI W,ANDERSON G,BARTOLUCCI A,et al.Chemotherapy in non-small cell lung cancer:a meta-analysis using updated data on individual patients from 52 randomised clinical trials[J].Br Med J,1995,311(7010):899-909.
  • 9MANDZIUK S,DUDZISZ-SLEDZ M,KORSZEN-PILECKA I,et al.Expression of P21 and Bcl-2 proteins in paraffin-embedded preparations of non-small cell lung cancer in stage ⅢA after Etoposide and Cisplatin induced chemotherapy[J].Ann Univ Mariae Curie Sklodowska[Med],2003,58(1):149-153.
  • 10HAN J Y,HONG E K,CHOI B G,et al.Death receptor-5 and Bcl-2 protein expression as predictors of tumor response to gemcitabine and cisplatin in patients with advanced non-small-cell lung cancer[J].Med Oncol,2003,20(4):355-362.

共引文献66

同被引文献60

引证文献8

二级引证文献69

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部