摘要
目的探讨患者治疗依从性对支气管哮喘(哮喘)预后的影响。方法随机选择我院2005～2010年住院及门诊哮喘患者68例,均建立医患联系卡,每周复诊,按照哮喘防治创议(G INA)方案选择长期控制相关药物进行阶梯性治疗,于治疗前及治疗3个月测定肺功能,采用呼气峰流速(PEF)和第一秒用力呼气容积(FEV1)占预计值的百分比作为观测指标。根据患者治疗依从程度分为研究组和对照组,治疗依从性好的34例纳入研究组,不规范用药的34例纳入对照组,比较两组病情转归。结果研究组没有因哮喘急性发作而急诊就医者,偶尔使用缓解药物1例(2.94%);对照组中不能坚持规范用药者28例(82.35%),其中用药剂量不准确23例(67.65%),用药方法不正确25例(73.53%),每月哮喘发作1次以上8例(23.53%),两组比较差异有统计学意义(χ2=4.61,P<0.05)。PEF%及FEV1%治疗前两组比较差异无统计学意义(P>0.05);治疗后PEF%及FEV1%均明显上升,但研究组更为明显,两组比较差异有统计学意义(P<0.01)。结论规范应用G INA方案,加强患者治疗依从性的干预,有助于提高哮喘治疗的效果。
Objective To investigate the effect of therapy compliance on prognosis of bronchial asthma.Methods 68 Inpatients and outpatients were randomly enrolled from 2005 to2010.The doctor-patient connection cards were all established,and return visits were performed to all the patients every week.Long-term control and ladder-related drugs treatment were applied to the patients according to GINA.The lung functions measured by PEF and FEV1% were detected before treatment and 3 months after.According to the degree of therapy compliance,34 patients with good therapy compliance were enrolled in the study group,and those with irregular drug using were enrolled in the control group.The prognosis of patients in the two groups were observed and compared.Results In the study group,there was no emergency case due to acute asthma attacks,only 1 case（2.94%） with occasional use of alleviator.While in the control group,28 cases（82.35%） could not adhere to the normative medication,among whom,23（67.65%） with inaccurate drug dosage,25（73.53%） with uncorrected treatment method,and 8（23.53%） with asthma attack for more than 1 month.There was significant difference between the two groups（χ2=4.61,P0.05）,but no significant difference in PEF% and FEV1% between the two groups before treatment（P0.05）,After treatment,both PEF% and FEV1% in the two groups were significantly increased,especially in the study group,and there was significant difference between the two groups（P0.01）.Conclusion Standardized application of GINA program to strengthen the therapy compliance of patients in asthma treatment may produce satisfactory prognosis results.
出处
《临床误诊误治》
2011年第4期12-14,共3页
Clinical Misdiagnosis & Mistherapy
关键词
哮喘
病人依从
药物疗法
治疗结果
Asthma
Patient compliance
Drug therapy
Treatment outcome
