摘要
目的分析温州市6岁以下婴幼儿腹泻轮状病毒的感染情况。方法利用胶体金法检测标本中A群轮状病毒抗原,用聚丙烯酰胺凝胶电泳进行核酸分型。结果 2007～2009年轮状病毒检测的阳性率分别为46.1%、42.7%、30.0%,在6个月～2岁腹泻患儿中检出率最高,最高达40%。每年的2月、5月和10～11月是感染的高峰期。引起婴幼儿腹泻的轮状病毒以长型为主,占94.4%,其中长型以L1型为主。结论轮状病毒是引起春秋季节6个月～2岁婴幼儿腹泻的主要病原体。轮状病毒不同电泳型引起的临床症状差异明显。
Objective To investigate the prevalence of infections caused by rotavirus among infants with diarrhea aged less than 6 years old in Wenzhou, China. Methods Colloidal gold test was used to detect the group A antigen of rotavirus. The genotypes of rotavirus were determined by polyacrylamide gel electrophoresis. Results The positive rates of rotavirus in 2007, 2008 and 2009 were 46.1% , 42.7% and 30.0% , respectively. The prevalence of rotavirus among infants with diarrhea aged from 6 months to 2 years was high to 40%. The peak of infection caused by rotavirus occurred in February, May, October and November of every year. Long type of rotavirus isolates causing infantile diarrhea accounted for 94.4% , in which the type L1 was the most prevalent type. Conclusion Rotavirus is the major pathogen causing infantile diarrhea of the patients aged from 6 months to 2 years in spring and autumn. Different electrophoresis types of rotavirus can cause different clinical symptoms.
出处
《医学研究杂志》
2011年第3期83-85,共3页
Journal of Medical Research
基金
温州市科技局项目(Y20070134)
