摘要
目的总结Beger及Frey手术的手术技巧及研究应用的新进展。方法分析、评价近年来Beger及Frey手术在胰腺良性疾病及低度恶性肿瘤中的应用技巧,并对其临床疗效研究进展的文献进行综述。结果随着器官保存观念被广泛接受,Beger及Frey手术被广泛应用,与传统标准术式比较,其具有保留消化道完整、切除胰腺组织少、手术创伤小、术后生存质量高及手术安全性好的优点,但是长期疗效优势随着时间延长而减弱。结论 Beger及Frey手术是相对安全、疗效确切的术式,可作为治疗胰腺良性疾病及低度恶性肿瘤特别是慢性胰腺炎的标准术式,但尚需进一步探索研究,降低术后并发症发生率及提高远期疗效。
Objective To review the current clinical application of Beger procedure and Frey procedure for benign disease or low-grade malignant potential lesion of pancreas.Methods Relevant literatures about current advance of clinical application of Beger procedure and Frey procedure published recently of domestic and abroad were collected and reviewed.Results With the concept of organ-preserving operations was adopted in recent years,Beger procedure and Frey procedure were applied generally.Beger procedure and Frey procedure were associated with tolerable perioperative risk,postoperative complications,and good outcomes in the aspects of preservation of function and curability in these lesions compared to conventional pancreatectomy,with preservation of the physiological food passage,thus patients gained weight faster,had less pain,and demonstrated better exocrine and endocrine pancreatic function postoperatively and an improvement in the quality of life.Both procedures had reached an international position as a standard operation for the treatment of benign disease or low-grade malignant potential lesion of pancreas.But after long-term following-up early advantages were no longer present.Conclusions Beger procedure and Frey procedure are safe and effective in providing good outcomes in the aspects of preservation of function and curability in benign disease or low-grade malignant potential lesion of pancreas.Organ-preserving pancreatectomy could become a new organ-preserving standard operation.
出处
《中国普外基础与临床杂志》
CAS
2011年第3期341-347,共7页
Chinese Journal of Bases and Clinics In General Surgery
关键词
保留十二指肠胰头切除术
胰腺囊性肿瘤
慢性胰腺炎
Duodenum-preserving pancreatic head resection
Pancreatic cystic neoplasm
Chronic pancreatitis
