摘要
目的:观察稻芽粗提物对变异链球菌的抑制作用。方法:采用醇提法制取稻芽的药物粗提物,并测量其在不同药物浓度下对变异链球菌生长、黏附、产酸等作用的抑制效果。结果:稻芽粗提物抑制变异链球菌(变链菌)体外生长的最低抑菌浓度(MIC)值为6.25 mg/mL,当稻芽粗提物浓度≥0.78 mg/mL时有较明显的抑制变链菌黏附的作用,当稻芽粗提物浓度≥0.39 mg/mL即有较明显的抑制变链菌产酸的作用。结论:稻芽粗提物对变异链球菌有一定的抑制作用。
AIM： To investigate the effect of Fructus oryzae germinates crude extracts on Streptococcus mutans.METHODS： Fructus oryzae germinatus was extracted by the ethanol method.The effect of Fructus oryzae germinates crude extracts on the growth,adherence and acid generation was assessed on S.mutans ATCC25175.RESULTS： The minimal inhibition concentration（MIC） of Fructus oryzae germinatus crude extracts on S.mutans was 6.25 mg/mL.Acid generation and adherence of S.mutans could be inhibited by a concentration of ≥0.39 mg/mL or 0.78mg/mL of the crude extracts,respectively.CONCLUSION： Fructus oryzae germinatus crude extracts showed inhibitory effect on S.mutans,indicating that Fructus oryzae germinatus may have anti-caries effect.
出处
《牙体牙髓牙周病学杂志》
CAS
北大核心
2011年第3期121-124,共4页
Chinese Journal of Conservative Dentistry
关键词
稻芽粗提物
变异链球菌
黏附
产酸
fructus oryzae germinates crude extracts
streptococcus mutans
adherence
acid generation
