摘要
建立了气相色谱/质谱联用(GC/MS)检测唇膏中二甘醇残留量的方法。样品经海砂研磨均匀、无水硫酸钠除水后,以甲醇超声提取,滤液直接检测。采用外标法,选择离子定量。二甘醇在10.0～1000.0mg/kg浓度范围内线性关系良好,相关系数(R2)为0.9994。在10～1000mg/kg添加水平的平均回收率为92.5%～106.9%,相对标准偏差(RSD)为3.5%～4.6%。实验表明,该方法适用于唇膏等化妆品中二甘醇残留量的检测。
The method for determination of residual diethylene glycol in lipstick by gas chromatography/mass spectrometry （GC/MS） was established. After grinding by sea sand, removing moisture by anhydrous sodium sulfate, the sample was ultrasonic extracted with methanol, then it was detected directly. Using external standard method and selecting ion quantification, the diethylene glycol had good linear relationship within concentrations between 10.0 to 1000. 00 mg/kg. And the correlation coefficient （R2） was 0. 999 4. In 10 - 1 000 mg/kg, the average recovery of added level was 92.5% - 106.9% and the relative standard deviation （RSD） was 3.5% - 4.6%. The results showed that the method is suitable for determination residual diethylene glycol in lipstick and other cosmetics.
出处
《香料香精化妆品》
CAS
2011年第2期35-37,共3页
Flavour Fragrance Cosmetics
关键词
二甘醇
气相色谱/质谱法
唇膏
化妆品
diethylene glycol gas chromatography/mass spectrometry lipstick cosmetic
