摘要
采用电化学聚合的方法将氨基黑10B染料分子修饰到玻碳电极表面,制备了聚氨基黑10B修饰电极,其稳定性和重复性较好。该修饰电极对维生素B6(VB6)的氧化有明显的电催化作用,VB6的氧化峰电位负移,电流显著增加。利用微分脉冲伏安和安培检测技术对VB6进行了定量检测,检测限均可达到0.05μmol/L,与已报道的修饰电极比较,是目前最低的。将该修饰电极用于不同药物制剂中VB6浓度的测定,操作方便、快速,方法灵敏,准确度高。
A poly（amino black 10B） modified glassy carbon electrode,prepared by electrochemical polymerization was developed for the direct determination of vitamin B6.The polymer thickness can be controlled by potential circles.The modified electrode shows obvious electrocatalytic activity toward the oxidation of vitamin B6,since it decreases the oxidation overpotential as well as greatly enhances the oxidation peak current of vitamin B6.Differential pulse voltammetry and amperometric detection methods were utilized for the measurement of vitamin B6.The method is very sensitive and simple,and the detection limit is 0.05 μmol/L.Compared with other known modified electrodes,the poly（amino black 10B） modified electrode possesses many advantages such as low detection limit,fast response,good repeatability,low cost and simplicity.The practical application of this modified electrode was demonstrated with vitamin B6 drugs.
出处
《应用化学》
CAS
CSCD
北大核心
2011年第5期590-596,共7页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金(20875085)资助项目
关键词
维生素B6
修饰电极
氨基黑10B
电催化
安培检测
Vitamin B6
modified electrode
amino black 10B
electrocatalysis
amperometric detection
