摘要
为研究胃癌患者血清铜、锌水平与组织学分化程度及分期的关系，对经病理确诊的１１０例胃癌患者血清铜、锌水平进行了测定。结果表明，Ⅳ期患者血清铜高于不足Ⅳ期患者，Ｐ＜００５；分化不良型胃癌中Ⅳ期者血清铜高于不足Ⅳ期者，Ｐ＜００５；分化型胃癌中Ⅳ期者血清铜与不足Ⅳ期者无显著性差异，Ｐ＞００５；Ⅳ期患者中分化不良型胃癌血清铜高于分化型胃癌，Ｐ＜００５；血清锌水平在不同分化程度及不同病期间未见明显差异，Ｐ＞００５。提示，胃癌患者血清铜水平与组织学分化程度有关，与病期亦有关。
To investigate the relationship between serum copper,zinc levels and degree of histological differentiation and stages in patients with gastric cancer,serum copper and zinc was determined in 110 patients with gastric cancer. The results showed that the copper level in patients with gastric cancer at Ⅳstage was higher significantly than that of the patients at less than Ⅳstage's gastric cancer, P <0 05;Among patients with low-differentiated gastric cancer,serum copper level of Ⅳstage's patients increased markedly compared to that of patient at less than Ⅳ stage's patients, P <0 05,but not in patients with high-differentiated gastric cancer;Among patients at Ⅳstage's gastric cancer,serum copper level of patients with low-differentiated gastric cancer was higher than that with high-differentiated gastric cancer, P <0 05;Serum zinc level had no significant difference among patients with a vary of differentiation and stage of gastric cancer.It suggested that serum copper level of patients was related to the histological differentiation and the stage of gastric cancer.
出处
《广东微量元素科学》
CAS
1999年第8期35-37,共3页
Trace Elements Science
关键词
胃癌
组织学
铜
锌
血清
分化
分期
Gastric cancer,Histopathology,Copper,Zinc.
