摘要
目的：比较临床常用的六项小气道功能测定方法对小气道功能异常的发现率。方法：健康体检者515例，用自动肺功能检测仪测定最大用力呼气中段流速（MMEF），最大用力呼气中段流量时间（FET25％～75％），50％及25％肺活量时最大用力呼气流速（V50，V25），三相斜率（△N／L），闭合气量（CV／VC％）等指标。结果：小气道功能异常的发现率最高的是△N／L（84．8％），FET25％～75％（83．4％），V25（72．8％），其余依次为MMEF（61．0％），CV／VC％（53．3％），V50（52．0％）。如将△N／L，FET25％～75％，V253项综合考虑，3项均异常时，小气道功能异常检出率仅为65．0％，△N／L与V25或FET25％～75％与△N／L2项均异常时，小气道功能异常检出率亦仅为71．8％和74．6％．3项中任何1项异常时，小气道功能异常检出率可达93．5％。结论：多项检测联合判断，对早期发现小气道功能异常的敏感性明显增加。
Objective: To compare the abnormal discovery rate of small airway functional disorders with6 tests of small airway functions. Methods: 515 normal subjects were examined with an automatic determination apparatus of pulmonary functions. Maximal mid-expiratory flow velocity (MMEF), maximal mid-expiratory flow time (FET25%~75% ), maximal mid-expiratory flow velocity in pulmonary vital capacity 50%and 25 % (V50 and V20),hN/L,and close volume/vital capacity (CV/VC% ) were determined. Results: Thehighest abnormal discovery rate of small airway disorders was 84. 8% for △N/L, 83. 4% for FET25%~75 %, 72. 8% for V25, 61. 0% for MMEF, 53. 3% for CV/VC% and 52. 0% for v50. The abnormal discovery rate was 65. 0% when △N/L, V25 and FET25%~75% were all abnormal, it was 74. 6% when 2 of the3 parameters were abnormal and it was 93. 5% when only one parameter of the 3 was abnormal. Conclusion:It is believed that in order to increase the sensitivity of small airway functional determinations, the combination of many parameters is recommended.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1999年第7期528-530,共3页
Journal of Third Military Medical University
