摘要
原发性肝癌是目前世界上致死率最高的恶性肿瘤之一,且发病率有逐年上升的趋势.血清肿瘤标志物对肝癌的早期诊断、肿瘤进展的监测、疗效判定、复发和患者生存率的判断具有重要意义,临床常用的实验室血清标志物有甲胎蛋白、异常凝血酶原、血清铁蛋白α-L岩藻糖苷酶、γ-谷氨酰转肽酶(GGT)及其同工酶、人高尔基蛋白73、磷脂酰肌醇蛋白聚糖-3、鳞状细胞癌抗原、铁蛋白及其酸性同工铁蛋白等.通过对这些实验室血清标志物检测,可以早期诊断肿瘤病变程度,并判定预后.
Primary hepatocellular carcinoma(HCC)is one of the malignant tumors with the highest death cause and increasing incidence.Serum tumor marker is very important significance for early diagnosis,tumor progression monitoring,therapeutic effect evaluation,tumors recurrence and patients'survival prediction.AFP,DCP,AFU,GGT,GP73,GPC-3,SCCA,and AIF are important markers which are commonly used in clinical diagnosis of liver cancer traditionally.The above markers can diagnose the tumors in the early period,tumor progression and evaluate prognosis.
出处
《北华大学学报(自然科学版)》
CAS
2011年第2期189-192,共4页
Journal of Beihua University(Natural Science)
关键词
原发性肝癌
诊断
肿瘤标志物
primary hepatocellular carcinoma
diagnosis
tumor markers