摘要
目的分析早产儿20项行为神经评分（NBNA）特点，探讨影响早产儿NBNA的危险因素。方法应用新生儿20项行为神经评价方法对我院274例纠正胎龄40周的早产儿进行评定，按NBNA评分分为NBNA正常组（n=221）和NBNA异常组（n=53）。回顾早产儿出生史、母亲孕产期情况、新生儿期原发疾病住院情况及检查结果，分析影响早产儿NBNA评分的可能危险因素。结果两组患儿在胎龄、出生体质量、头围、身长、Apgar评分，复苏时间、住院时间、达完全胃肠营养时间方面比较差异有统计学意义（P〈0．05）；多胎、肺透明膜病、出血性和缺氧性脑损伤、严重感染、低血糖、高胆红素血症、慢性肺疾病的发生率两组比较差异有统计学意义（P〈0．05）；而性别、产前使用激素、贫血、低血压及听觉通路异常情况两组比较差异无统计学意义（P〉0．05）。窒息、低出生体质量、肺透明膜病、出血性和缺氧性脑损伤、严重感染、高胆红素血症、反复低血糖及慢性肺疾病是影响早产儿NBNA评分的危险因素。结论早产儿生后虽纠正胎龄足月，但在行为能力和主动肌张力方面得分仍低。低Apgar评分、低出生体质量、肺透明膜病、出血性和缺氧性脑损伤、严重感染、高胆红素血症、反复低血糖及慢性肺部疾病与早产儿NBNA评分密切相关。
Objective To analyze the characteristic of twenty-item premature behavioral neurological assessment, and to assess the risk factors of neonatal behavioral neurological assessment（NBNA） in premature infants. Methods Total two hundred and seventy-four premature infants hospitalized in Guangzhou Children＇s Hospital were assessed with the NBNA after correcting age 40 weeks,premature infants were divided into two groups：normal group （n =221 ） and abnormal group （n =53） according to NBNA. The birth history, mother pregnancy situation, the disease during neonatal period and results in hospital were reviewed, and the risk factors of NBNA in premature infants were assessed. Results There were significant differences in gestational age, birth weight, head circumference, body height, Apgar score, resuscitation time, hospitalization time and total gastrointestinal nutrition time between the two groups（ P 〈 0. 05 ）. The incidences of superfoetation,hyaline membrane disease, hemorrhagic and hypoxic brain injury, severe infection, hyperbilirubinemia, hypoglycemia and chronic lung disease were different between the two groups （P 〈 0.05 ）. There were no differences in gender, antenatal hormone use, anaemia,hypotension and evoked potential abnormality（ P 〉 0. 05 ）. Multivariate logistic regression analysis showed that the risk factors of NBNA score in premature infants would include low Apgar score, low birth weight, hyaline membrane disease, hemorrhagic and hypoxic brain injury, severe infection, hyperbilirubinemia, hypoglycemia and chronic lung disease. Conclusion Although the premature infants corrected age 40 weeks, but the capability and initiative muscular tension are still lower than term infant. Low Apgar score, low birth weight, hyaline membrane disease, hemorrhagic and hypoxic brain injury, severe infection ,hyperbilirubinemia,hypoglycemia and chronic lung disease are important risk factors related to premature behavioral neurological assessment.
出处
《中国小儿急救医学》
CAS
2011年第2期116-119,共4页
Chinese Pediatric Emergency Medicine
基金
广州市科技攻关计划重大项目（200521-E0103）
关键词
行为神经评分
危险因素
早产儿
Behavioral neurological assessment
Risk factors
Infant, premature
