摘要
目的:探讨高血压病合并无症状高尿酸血症患者的临床特征,高尿酸血症与高血压之间的关系。方法:68例老年高血压患者为观察组,78例健康体检者为对照组,测定血浆尿酸、甘油三酯、高密度脂蛋白胆固醇,体重指数,询问生活方式。结果:416例高血压病患者中检出合并高尿酸血症68例,占16.35%。观察组的高血压病分级有2级41例和3级23例,占94.12%,血尿酸与血甘油三酯水平之间呈低度显著正相关(r为0.19,P<0.01);血尿酸与血高密度脂蛋白水平之间呈低度显著负相关(r为-0.209,P<0.01);血尿酸与体重指数之间呈中度显著正相关(r为0.254,P<0.01)。结论:高尿酸血症是反映高血压病患者病情严重程度的一个重要指标,可作为高血压患者的常规检查项目,高血压病合并无症状高尿酸血症患者应改善生活方式。
Objective To investigate the relationship between hypertension and hyperuricemia and to observe the clinical features of hypertensive patients with asymptomatic hyperuricemia.Methods 68 cases of hypertensive patients with asymptomatic hyperuricemia as observation group and 78 cases of healthy people as control group were investigated with uric acid,triglyeride,high density lipoprotein cholesterol.Their body mass index（BMI）was computed and lifestyles were investigated.Results There were 68 cases of complicating hyperuricemia among 416 cases of hypertensive patients,accounting for 16.35%.In the observation group there were 41cases of stage two hypertension and 23cases of stage three hypertension,accounting for 94.12%. There was a low positive correlation（r=0.19,P0.01）between serum uric acid and triglyeride of plasma in hypertensive patients.There was a low negative correlation（r=-0.209,P0.01）between serum uric acid and high density lipoprotein cholesterol of plasma and a middle positive correlation（r=0.254,P0.01）between serum uric acid and body mass index in those patients.Conclusion The fact shows that hyperuricemia in hypertensive patients is an useful and an important parameter of clinical observation in hypertension.Routine examination of uric acid of plasma should be carried out in hypertensive patients.Improvement of lifestyles in hypertensive patients with asymptomatic hyperuricemia should be suggested.
出处
《中国农村卫生事业管理》
2011年第3期320-322,共3页
Chinese Rural Health Service Administration
关键词
高血压病
高尿酸血症
血尿酸
血脂代谢异常
hypertension
hyperuricemia
uric acid of plasma
abnormality of lipid metabolism
