摘要
目的提高原发性醛固酮增多症的诊治水平。方法分析１９７８～１９９８年收治的原发性醛固酮增多症１４６例，其中肾上腺腺瘤１１１例（７６％），肾上腺增生３５例（２４％），均经手术和病理证实。结果术后肾上腺腺瘤８２例（８２／１１１），肾上腺增生１６例（１６／３５），血压恢复正常，所有病人血钾均恢复正常。结论正确的治疗取决于正确的定性诊断，分型和定位诊断，Ｂ超和ＣＴ是原醛症定位诊断的主要方法，开放性手术是主要的治疗手段。影响疗效的因素，主要与患者年龄大、病史长、周身血管硬化有关。
Objective To present and evaluate the diagnosis and treatment of 146 cases of primary aldosteronism. MethodsFrom 1978 to 1998,146 cases of primary aldosteronism were diagnosed and treated of which 111 were caused by adrenal adenoma (76%) and 35 by adrenal hyperplasia (24%).The diagnosis was all ascertained on open surgery and pathological studies.Hypertension and hypokalemia were the cardinal clinical manifestations.Plasma aldosterone level was elevated in all the 126 cases examined and plasma renin decreased in the 97 cases examined.The positive diagnosis rate of Bultrasonography was 67% and that of CT 96%. Results In 82 cases of adrenal adenoma out of 111 (73.2%) and 16 cases of adrenal hyperplasia out of 35 (45.7%),the blood pressure dropped and the serum potassium level elevated to normal range after open surgery. ConclusionsAppropriate treatment depends on correct qualitative diagnosis and localization of the causative lesion.Bultrasonography and CT scan play the important role in diagnosis.Open surgery is the main treatment method.Factors effecting the therapeutic outcome are the age and the status of vascular sclerosis of the patient and the medical history.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1999年第8期459-461,共3页
Chinese Journal of Urology
