摘要
目的观察高压氧对急性重度一氧化碳中毒患者血浆β－内啡肽（β－ＥＰ）含量的影响。方法对１２名急性重度一氧化碳中毒的患者分别于高压氧治疗（ＨＢＯ）前，３次和１０次后，评定Ｇｌａｓｇｏｗ分数，并测定血浆β－ＥＰ的含量。结果ＨＢＯ治疗３次后，患者Ｇｌａｓｇｏｗ评分明显增大，由５．６±２．２增加至１４．０±２．７（Ｐ＜０．０１），血浆β－ＥＰ明显减少，由（２４７．７±１７２．８）μｇ／Ｌ减至（１２２．６±１０７．３）μｇ／Ｌ（Ｐ＜０．０１）。结论患者血浆β－ＥＰ含量可以作为一氧化碳中毒疗效的一项指标。
Objective To study the content of plasma β-endophin in acute severe CO poisoning patients treated with hyperbaric oxygneation(HBO). Methods The Glasgow scale and the content of β-endophin of 12 patients with severe CO poisoning were measured before and after the 3rd and 10th times of HBO therapy. Results The data showed that the Glasgow scale after 3 times of HBO therapy was obviously increased (5.6±2.2 up to 14.0±2.7) than that of before HBO treatment(P<0.01).At the same time,the content of plasma β-endophin was markedly decreased (247.7±172.8)μg/L down to (122.6±107.3)μg/L too.Conclusion It is indicated that the plasma β-endophin content can be as an index for the effect of HBO on acute CO poisoning.
出处
《中华理疗杂志》
1999年第4期203-204,共2页
Chinese Journal of Physical Therapy
关键词
一氧化碳中毒
Β内啡肽
高压氧治疗
Hyperbaric oxygenation Carbon monoxide poisoning Beta-endophin
