摘要
2-苯基-1,2,3-连三唑-4-甲酰肼(1)与芳酸在POCl_3催化下得到6种新的2-芳基-5-(2’-苯基-1’,2’,3’-连三唑-4’-基)-1,3,4-噁二唑(2)。1与羰基化合物缩合得到相应的酰腙(3),在Ac_2O作用下环化成2-取代基-3-乙酰基-5-(2’-苯基-1’,2’,3’-连三唑-4’-基)-1,3,4-噁二唑啉(4)。化合物的结构经元素分析,IR,~1H NMR和MS确证。
By the condensation of 2 - Phenyl - 1,2,3- triazole - 4 - formyl hydrazide (1) with substituted benzoic acids in the presence of phosphorus oxychloride,six novel 2 - Aryl - 5 - (2' - Phenyl - 1' ,2' ,3' - triazole -4' -yl) - 1,3,4- oxadiazoles (2) were obtained. Reaction of acid hydrazide (1) with keto compounds gives corresponding hydrazones (3),which could be readily converted to their congener oxadiazolines (4) in good yields by treatment with Ac2O. Their structures were established by elemental analysis, IR,1H NMR and MS spectroscopy.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
1999年第3期316-320,共5页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金
新疆大学自然科学基金
关键词
苯基
连三唑
恶二唑
恶二唑啉
合成
2 - phenyl -1,2,3- triazole ,1,3,4- Oxadiazole ,1,3,4- Oxadiazoline
