摘要
1例44岁男性患者,椎管内神经鞘瘤术后给予头孢替安,复方甘露醇,并给予奥拉西坦4.0 g溶于5%葡萄糖注射液250 ml中静脉滴注。奥拉西坦开始滴注后约15 min患者出现全身抽搐,大汗淋漓,面部及四肢末梢发绀。立即停药,给予面罩吸氧。心电监护示血压90/60 mm Hg(1 mmHg=0.133 kPa),脉搏120次/min。给予肾上腺素1 mg静脉推注,0.9%氯化钠注射液500 ml快速滴注。10 min后血压80/50 mm Hg,血氧饱和度0.90。再次静脉推注肾上腺素1 mg,地塞米松5 mg。20 min后患者抽搐等症状缓解,血压升至100/75 mm Hg。
A 44-year-old man received cefotiam,compound mannitol,followed by an IV infusion of oxiracetam 4.0 g dissolved in 5% glucose 250 ml after undergoing surgery for intraspinal neurilemma.About 15 minutes after oxiracetam infusion start,the patient experienced convulsion,diaphoresis accompanied by facial and peripheral cyanosis.Oxiracetam was discontinued and he was given mask oxygen.ECG monitoring revealed a blood pressure of 90/60 mm Hg and a heart rate of 120 beats/min.Adrenaline 1 mg was given by IV push,and then a rapid IV infusion of 0.9% sodium chloride injection 500 ml was administered.Ten minutes later,his blood pressure decreased to 80/50 mm Hg and his oxygen saturation was 0.90.He received an IV push of adrenaline 1 mg and dexamethasone 5 mg again.Twenty minutes later,the patient＇s convulsions disappeared and his blood pressure increased to 100/75 mm Hg.
出处
《药物不良反应杂志》
2011年第1期50-50,共1页
Adverse Drug Reactions Journal
