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角化棘皮瘤24例临床病理分析 被引量:1

Keratoacanthoma:a clinicopathological study of 24 cases
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摘要 目的:探讨角化棘皮瘤的临床病理特征及鉴别诊断。方法:对24例角化棘皮瘤临床资料、组织病理学特征进行分析,并结合文献进行讨论。结果:发生于臀部1例,鼻前庭1例,其余均发生于曝光部位,均为单发型。肿瘤呈半球状突出于皮肤表面,中央充满角质栓,似"火山口"样,边缘有唇状表皮包绕。结论:角化棘皮瘤的诊断依据特征性的临床与病理特点,应与皮肤鳞状细胞癌相鉴别,局部完整切除皮损预后较好。 Objective:To explore the clinicopathologic features and differential diagnosis of keratoacanthoma. Methods:Clinical data and histopathological features of twenty-four cases bearing keratoacanthoma were retrospectively analyzed and discussed with review of the literature. Results:Except one case occurred in the hip,and 1 case in the nasal vestibule,all the rest occurred in the sun-exposed areas and were solitary type.Tumors were protruding from the skin surface as hemispherical and the central bolt was full of horny,like volcano,edge-like skin surrounding the lips. Conclusions:Diagnosis of keratoacanthoma depend on the characteristic clinical and pathological features.Differential diagnosis should be addressed in the case of squamous cell carcinoma in skin.Good prognosis could be achieved by completely resection of the local lesion.
出处 《蚌埠医学院学报》 CAS 2011年第3期255-257,共3页 Journal of Bengbu Medical College
关键词 皮肤肿瘤 角化棘皮瘤 鳞状细胞 病理学 临床 诊断 鉴别 skin neoplasms keratoacanthoma carcinoma squamous cell pathology clinical
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  • 1左连富,周道安,齐风英,郭建文,刘江惠.定量分析乳腺癌细胞P^(53)基因产物的表达[J].中华物理医学杂志,1994,16(2):78-80. 被引量:18
  • 2李承明,单维华.角化棘皮瘤[J].国外医学(皮肤性病学分册),1995,21(2):99-102. 被引量:9
  • 3王建力,陈莉.P53基因蛋白在皮肤鳞癌中的表达[J].中国皮肤性病学杂志,1996,10(5):269-270. 被引量:3
  • 4Kossard S, Tan KB, Choy C. Keratoacanthoma and infundibulocystic squamous cell carcinoma[ J ]. Am J Dermatopathol, 2008,30 (2) :127 134.
  • 5Perez M, Robins P,Biria S, et al. p53 oncoprotein expression and gene mutations in some keratoaeanthomas I J]. Arch Dermatol, 1997,133(2) : 189 - 193.
  • 6Kerschmann RL, McCalmont TH, Leboit PE. p53 oncoprotein expression and proliferation index in keratoacanthoma and squamous cell carcinoma[J]. Arch Dermatopathol,1994,130:181 - 186.
  • 7Sleater JP,Beers BB,Stephens CA,et al. Keratoacanthoma:A deficient squamous cell carcinoma? Study of bel- 2 expression[J]. J Cutan Pathol, 1994,21(6) :514 - 519.
  • 8Bergman R, Amichai B, Kilim S, et al. An immunohistochemical study of bcl - 2 protein expression in keratoacanthoma, as compared to squamous-cell carcinoma and basal-cell carcinoma[ J ]. Am J Dermatopathol, 1997,19(5) : 506.
  • 9Tkach JR,Thorne EG. Keratoacanthoma of the glans penis [ J ]. Cutis,1979 ,24(6) :615 -616.
  • 10李恭会 李新德.阴茎角化棘皮瘤恶变1例[J].浙江大学学报:医学版,2000,29(6):244-244.

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  • 1丁海峰,赵天恩,卢宪梅.角化棘皮瘤研究进展[J].中国麻风皮肤病杂志,2005,21(6):465-467. 被引量:17
  • 2陈健,鲁洁琼.角化棘皮瘤及癌变15例临床病理分析[J].浙江医学,2005,27(6):442-443. 被引量:3
  • 3崔炳南,李理,卢建新,庞然.阴茎角化棘皮瘤1例[J].中国皮肤性病学杂志,2005,19(7):443-444. 被引量:8
  • 4李承明,单维华.角化棘皮瘤[J].国外医学(皮肤性病学分册),1995,21(2):99-102. 被引量:9
  • 5Nascimento MC, Cominos D, Davies N J, et al. Vulval Keratoa- canthoma: a case report [J]. Gynecol Oneol, 2005, 97(2): 674- 676.
  • 6Choi JH, Shin DH, Shin DS, et al. Subungaml keratoacanthoma: ultrasound and magnetic resonance imaging findings[J]. Skeletal Radiol, 2007,36(8): 769-772.
  • 7Weedon DD, Malo J, Brooks D, et al. Squamous cell carcinoma arising in keratoacanthoma: a neglected phenomenon in the el- derly[J]. Am J Dermatopathol, 2010, 32(5): 423-426.
  • 8Godbolt AM, Sullivan J J, Weedon 1). Keratoacanthoma with per- ineural invasion: a report of 40 cases[J]. Australas J Dermatol, 2001, 42(3): 168-171.
  • 9Schwartz RA. Keratoacanthoma[J]. J Am Acad Dermatol, 1994, 30(1): 1-19.
  • 10栾菁,吴文育,陈淑君,林尽染,陈忠清.角化棘皮瘤70例临床分析[J].实用医院临床杂志,2009,6(2):42-43. 被引量:3

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