摘要
淋巴管畸形是一种常见的脉管畸形。硬化治疗是一种常用的治疗方法,临床将其作为一线治疗均获得较满意的疗效且无明显并发症。目前应用的硬化剂种类繁多,但没有一种能适应于所有病变。由于病变类型不同及使用的硬化剂不同,回顾性研究的结果也不一致。较多的临床研究表明,大囊型淋巴管畸形硬化治疗的疗效优于微囊型,对于大囊型病变或以大囊成分为主的混合型病变建议应用OK432或平阳霉素治疗,而微囊型病变则可选用强力霉素或平阳霉素。弥漫性微囊型淋巴管畸形的治疗仍然是一项具有挑战性的工作,常需硬化治疗与手术或激光治疗相结合。有关淋巴管畸形尤其是微囊型病变的硬化治疗药物及治疗方法尚需进一步研究。
Lymphatic malformations are common vascular anomalies in the head and neck.Percutaneous sclerotherapy of lymphatic malformations as the first-line treatment has been widely used and had satisfactory outcomes without severe complications in most of the cases.Many sclerosants have clinically been applied,but none of them can cure all malformations.Results vary from series to series,which probably reflect the complexity of lymphatic malformations and the varieties of sclerosing agents are in use.It is recommended that macrocystic or mixed lesions with larger cyst cavity can be treated by intralesional injection of OK-432 or pinyangmycin,and microcystic type is sclerosed applying doxycycline or pinyangmycin.The management of extensive lymphatic malformations in the head and neck regions is still challenging, usually in combination with surgical excision and laser.The better sclerosants and sclerosant techniques should be developed especially in management of microcystic lymphatic malformations.
出处
《口腔颌面外科杂志》
CAS
2011年第1期1-6,共6页
Journal of Oral and Maxillofacial Surgery
关键词
淋巴管畸形
硬化治疗
硬化剂
lymphatic malformations
sclerotherapy
sclerosants
