摘要
目的探讨原发性高血压患者肾动脉血流指标变化的临床意义。方法2006年5月至2010年7月我院门诊及住院的原发性高血压患者90例，其中1、2、3级高血压各30例，另选30名健康查体者作为健康对照组，应用彩色多普勒超声检测各组研究对象的双侧主肾动脉、段动脉和叶间动脉的血流频谱，获得各组血流参数，包括收缩期最大血流速度（Vmax）、舒张末期最低血流速度（Vmin）、舒张末期最低血流速度／收缩期最大血流速度（Vmin／Vmax）、阻力指数，并进行比较分析。结果健康对照组主。肾动脉的Vmax、Vmin、Vmin／Vmax及阻力指数分别为（63．99±7．68）cm／s、（23．86±3．07）cm／s，0．38±0．05、0．62±0．05；段动脉的Vmax、Vmin、Vmin／Vmax及阻力指数分别为（52．93±4．24）cm／s、（20．89±2．47）cm／s，0．40±0．04、0．60±0．04；叶间动脉的Vmax、Vmin、Vmin／Vmax及阻力指数分别为（35．32±4．22）cm／s、（15．07±2．54）cm／s，0．43±0．04、0．57±0．04。与健康对照组比较，1级高血压组仅叶间动脉的Vmin、Vmax／Vmin降低，阻力指数增高，差异具有统计学意义（P均〈0．05）；2级高血压组除主肾动脉的Vmax外，其余各。肾动脉的血流参数差异均有统计学意义（P〈0．05或0．01）；3级高血压组各级肾动脉的各项血流参数差异均有统计学意义（P〈0．05或0．01）；Vmax、Vmin及Vmin／Vmax随着血压分级的增加而减低，阻力指数随着血压分级的增加而升高。结论彩色多普勒超声。肾动脉血流动力学指标可为临床评价高血压患者。肾损害提供一定的依据。
Objective To explore the clinical significance of the changes of renal artery blood stream parameters in patients with essential hypertensive by color Doppler uhrasonography. Methods Ninety patients with essential hypertension were enrolled and divided into three groups （grade 1,2,3 ） according to their clinical blood pressure from May 2006 to July 2010 and each group included 30 cases. Thirty normal individuals were assigned to the control group. Color Doppler uhrasonography was used to determine the blood flow spectrum of bilateral main renal arteries, segmental arteries and interlobar arteries of kidneys. The parameters included Vmax, Vmin, Vmin/Vmax, resistance index （RI） were recorded and analyzed. Results In the control group, the Vmax, Vmin, Vmin/Vmax and RI in main renal arteries were （ 63.99 ± 7.68 ） cm/s, （ 23.86 ± 3.07 ） cm/s, 0. 38 ± 0.05 and 0. 62 ± 0. 05 ; in segmental arteries were （ 52. 93 ± 4. 24 ） cm/s, （ 20. 89 ± 2. 47 ） cm/s, 0.40 ± 0. 04 and 0. 60 ±0.04;in interlobar arteries were （35.32 ±4. 22） cm/s, （ 15.07 ±2. 54） cm/s,0. 43 ±0. 04 and 0. 57 ＋ 0. 04. Compared to the control, only Vmin, Vmin/Vmax and RI in interlobar arteries were statistically changed in grade 1 hypertension group （ P 〈 0. 05 ）. While in grade 2 hypertension group, all the blood flow parameters except Vmax in main renal arteries statistically changed compared to the control group （P 〈 0. 05 ）. In grade 3 hypertension group, all the blood flow parameters showed statistically differences when compared to control group （ P 〈 0.05 ）. The Vmax, Vmin, Vmin/Vmax decreased along with the blood pressure increased, however,the RI increased along with BP. Conclusion The renal artery blood stream parameters determined by color Doppler uhrasonography can provide important information to evaluate abnormal renal function in patients with hypertension.
出处
《中国综合临床》
2011年第3期261-264,共4页
Clinical Medicine of China
关键词
原发性高血压
血流动力学
彩色多普勒
Essential Hypertension
Hemodynamics
Color Doppler ultrasonography
