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亲环素A与CD147的相互作用及其临床意义 被引量：3

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摘要 亲环素A（cyclophilin A,CyPA）是一种在生物界广泛存在、高度保守的蛋白质,具有肽酰脯氨酰顺反异构酶（peptidel prolyl cis-trans isomersae, PPIase）,参与蛋白质折叠、组装与运输,它在细胞内能与环孢素A（cyclosporin A, CsA）结合,参与免疫抑制,还可介导胆固醇转运,能发挥前炎性因子的功能,并在信号传导中具有重要作用.CD147是一种广泛表达于人体多种组织的跨膜糖蛋白,属于免疫球蛋白超家族.
作者 李蓉（综述） 蔡辉（审校）
机构地区 南京军区总医院中西医结合科
出处 《医学临床研究》 CAS 2011年第2期362-366,共5页 Journal of Clinical Research
关键词 环孢菌素 抗原 肿瘤相关 碳水化合物 综述文献
分类号 R979.5 [医药卫生—药品]
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同被引文献40

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医学临床研究
2011年 第2期

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