摘要
复杂生物组织中光传输的精确模拟一直是组织光学的研究热点。利用新近发布的光在体素化三维结构组织中传输的蒙特-卡罗模拟软件(MCVM),采用目前国际上分辨率最高的人体结构数据集,模拟光在人体前臂组织中的传输,得到了组织中光吸收量的分布信息和空间分布特征,探讨了前臂组织的三维解剖结构对光传输和分布的影响。结果显示,三维解剖结构对光传输和分布有显著影响;相比于前人普遍采用光在多层组织中传输的蒙特-卡罗模拟软件(MCML)和层状模型所得的模拟结果,能更真实地反映光的传输和分布。该研究可为光动力疗法(PDT)、红外疗法等光保健与治疗技术提供定量的参考信息,具有一定的临床价值。
Accurate simulation of light propagation in complicated biological tissues has been a research focus of tissue optics.By utilizing the latest published Monte Carlo software-Monte Carlo modeling of photon migration in voxelized media（MCVM）,with the human structure database of the highest resolution in the world.It is obtained the distribution of the absorption in the forearm and the effect on light transport and distribution.The results indicated that the three-dimensional anatomic structrue influences the light transport and distribution obviously,and the simulation results were much closer to the real state by comparing with the results obtained previously by MCML（the Monte Carlo Modeling of light transport in multi-layered tissues） and layered tissue model.So the analysis provide the guidance to optical health care techniques,such as photodynamic therary and infrared therapy.
出处
《光学学报》
EI
CAS
CSCD
北大核心
2011年第3期189-193,共5页
Acta Optica Sinica
基金
国家自然科学基金(60828009)
教育部长江学者和创新团队发展计划资助课题
关键词
医用光学
光吸收量分布
蒙特-卡罗模拟软件(MCVM)
前臂光动力治疗
medical optics
absorption dose distribution
Monte Carlo software-Monte Carlo modeling of photon migration in voxelized media（MCVM）
forearm
photodynamic therapy
