藻酸双脂钠联合非诺贝特治疗2型糖尿病合并严重高甘油三酯血症76例分析
Efficacy of alginic sodium diester plus fenofibrate in type 2 diabetes complicated with severe hypertriglyceridemia and on insulin resistance.
摘要
2型糖尿病(T2DM)发病的中心环节是糖代谢紊乱,同时脂肪代谢也出现异常。本文通过观察联合应用藻酸双脂钠和非诺贝特治疗T2DM合并严重高甘油三酯(TG)血症患者的临床疗效,探讨其对血脂及胰岛素抵抗的影响。
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第3期224-225,共2页
Chinese Journal of Practical Internal Medicine
参考文献3
-
1Lee YM, Ravazzola M, Park BH, et al. Metabolic mechanisms of failure of intraportally transplanted pancreatic β-cells in tats role of lipotoxicity and prevention by leptin [ J ]. Diabetes, 2007,56 : 2295.
-
2黄泽锋,田慧,邵迎红,曹秀堂,李春霖,李剑,方福生,钟文雯,潘长玉,陆菊明.老年血脂紊乱与代谢综合征及心、脑血管事件相关性研究[J].解放军医学杂志,2007,32(10):1006-1006. 被引量:18
-
3曹惠君,刘国树.HDL-C/TG比值与老年高血压患者心血管危险的相关性研究[J].解放军医学杂志,2009,34(7):878-880. 被引量:5
二级参考文献13
-
1中华医学会糖尿病学分会代谢综合征研究协作组.中华医学会糖尿病学分会关于代谢综合征的建议[J].中国糖尿病杂志,2004,12(3):156-161. 被引量:3089
-
2杨文英,邢小燕,林红,马晓华,胡英华,李光伟,潘孝仁.高甘油三酯血症是非胰岛素依赖型糖尿病发病的危险因素──432例非糖尿病人群六年前瞻性观察[J].中华内科杂志,1995,34(9):583-586. 被引量:143
-
3Mancia G, De Backer G, Dominiczak A, et al. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens, 2007, 25(6), 1105.
-
4[No authors listed]. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancent, 1994, 344(8934): 1383.
-
5[No authors listed]. Prevention of cardiovascular events and death with pravastafin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group.N Engl J Med, 1998, 339(19):1349.
-
6Heart Protection Study Collaborative Group.MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randornised placebo-controlled trial. Lancet, 2002, 360(9326) : 7.
-
7Sever PS, Dahlof B, Pouher NR, et al.Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo- Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet, 2003, 361 (9364): 1149.
-
8Yuan G,Al-Shali KZ,Hegele RA.Hypertriglyceridemia:its etiology,effects and treatment.CMAJ,2007,176(8):1113.
-
9Hokanson JE,Austin MA.Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level:a meta-analysis of population-based prospective studies.J Cardiovasc Risk,1996,3(2):213.
-
10St-Pierre J,Lemieux I,Perron P,et al.Relation of the “hypertriglyceridemic waist” phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus.Am J Cardiol,2007,99(3):369.
共引文献20
-
1朱智明.代谢综合征的“积木效应”[J].人民军医,2008,51(12):780-781. 被引量:1
-
2朱智明,杨晔.代谢综合征与心血管疾病[J].人民军医,2008,51(11):715-716. 被引量:10
-
3王起,戚晓昆.代谢综合征与脑血管疾病[J].人民军医,2008,51(11):717-717.
-
4刘韫宁,郭秀花,张普洪,王虹,王玮,刘颖颖,刘娟.离散二水平模型探讨代谢综合征血脂高密度脂蛋白胆固醇异常的影响因素[J].中国预防医学杂志,2010,11(2):175-177. 被引量:1
-
5秦登优,邓华聪,艾艳琴,糜公仆,李永玲.不同糖耐量个体游离脂肪酸、脂联素与胰岛β细胞功能的关系探讨[J].解放军医学杂志,2010,35(5):576-579. 被引量:6
-
6卢细娇,潘海林.代谢综合征内皮功能紊乱与大血管病变的研究进展[J].医学综述,2010,16(11):1705-1708. 被引量:8
-
7刘伟芳,陈利强,邹慧英,吴伟琼,许美伦,温红,吕汉文.高血压人群伴发代谢紊乱的现状及特点[J].中国医药指南,2010,8(24):5-7. 被引量:3
-
8丁晓东,范建高.肥胖症与肝病[J].中国实用内科杂志,2011,31(9):661-663. 被引量:4
-
9珠勒皮亚.司马义,陈玉岚,布海力且木.买买提.血清高密度脂蛋白水平与原发性高血压预后的关系研究[J].重庆医学,2013,42(8):869-871. 被引量:12
-
10汤振源,王燕,张勇.苏州市润达社区老年人血脂水平[J].中国老年学杂志,2013,33(11):2671-2672. 被引量:4
-
1代淑美,吕景文.藻酸双脂钠治疗糖尿病合并高脂血症的临床观察[J].长春医药,1995,8(2):20-21.
-
2陈淑玲,缪希文,付洪波.藻酸双脂钠与酚妥拉明联合治疗肺心病急性发作临床观察[J].河北医学,1996,2(6):627-628.
-
3林群英,周禾.巯甲丙脯酸、藻酸双脂钠治疗59例慢性肺心病心衰疗效观察[J].海峡药学,1994,6(2):26-27.
-
4王建功,孙晋芳.藻酸双脂钠、刺五加联合治疗糖尿病周围神经病变疗效观察[J].中国社区医师(医学专业),2005,7(17):33-33.
-
5李强,罗柳苏.藻酸双脂钠治疗不稳定型心绞痛疗效观察[J].中外医疗,2009,28(2):99-99.
-
6谢利蓉,周桂兰.刺五加联合藻酸双脂钠治疗不稳定性心绞痛临床分析[J].四川医学,2005,26(5):542-543. 被引量:1
-
7李娟,李毅.巯甲丙脯酸和藻酸双脂钠治疗慢性肺心病效果观察[J].河南诊断与治疗杂志,2000,14(4):211-212. 被引量:1
-
8张蕾,刘书芬.藻酸双脂钠治疗慢性肺心病30例血流变检测指标临床意义[J].哈尔滨医药,1996,16(1):13-13.
-
9杨向方,侯秀昌.藻酸双脂钠治疗高脂血症高粘血症64例临床观察[J].新乡医学院学报,2003,20(5):362-363. 被引量:3
-
10吕俊,刘桂华.辛伐他汀联合藻酸双脂钠治疗血脂异常的临床观察[J].常州实用医学,2008,24(4):232-233.