摘要
目的探讨国产药物洗脱支架在冠状动脉粥样硬化性心脏病(冠心病)复杂病变患者中应用的安全性及临床疗效。方法将215例确诊为冠心病的患者分为3组:单枚支架植入组(n=75)、两支架植入组(n=72)和多枚(≥3枚)支架植入组(n=68),术后长期随访,观察术后12个月随访终点时支架内再狭窄发生率及主要心血管事件(包括死亡、急性心肌梗死、靶血管再成形等)发生率。结果 215例患者经皮冠状动脉介入治疗均成功。介入治疗12个月随访结果显示,多支架组与两支架组和单支架组比较,支架内再狭窄及主要心血管事件发生率比较,差异均无统计学意义(P>0.05)。结论多枚国产药物支架植入在复杂冠心病患者中应用安全、有效。
Objectives To assess the efficacy and safety of implantation of homemade drug-eluting stents in patients with complicated coronary artery disease. Methods According to the stent number, 215 patients with coronary artery disease from March 2004 to March 2009 were divided into three groups： single stent group （OS group,n=75）;two stents group （TS group,n=72） ; ≥3 stents group （MS group,n=68）. The occurrence rate of in-stent restenosis （ISR） and major adverse cardiovascular event （sudden death, reinfarction, revascularization） were analysed after 12 months of implantation. Results Three groups showed a success rate of 100% in stenting. There were no statistic difference on aspect of ISR and on aspect of major adverse cardiovascular event （P〉0.05） after 12 months of implantation. Conclusions Implantation of multiple drug-eluting stents does not increase the risk of restenosis or major adverse cardiovascular event, and it is comparable safety and efficacy with implantation of single and two stents.
出处
《岭南心血管病杂志》
2011年第1期33-35,共3页
South China Journal of Cardiovascular Diseases
关键词
冠状动脉疾病
药物洗脱支架
支架内再狭窄
主要心血管事件
coronary artery disease
drug-eluting stent
in-stent restenosis
major adverse cardiovascular event
