摘要
目的分析嗜酸细胞性胃肠炎(EG)的临床特点、诊断要点及临床治疗情况。方法回顾性分析7例EG患者的临床资料。重点分析患者的临床表现、实验室检查、内镜检查、病理检查、临床治疗等情况。结果 EG患者临床均出现腹痛症状,黏膜型患者常以腹痛、腹胀、恶心为主要表现,肌层型以肠梗阻为主要表现,浆膜型以腹痛、腹胀、腹水为主要症状。5例患者外周血嗜酸粒细胞计数升高,内镜下可见黏膜充血、糜烂、出血、溃疡,病理可见大量嗜酸细胞浸润。激素治疗非浆膜型患者可在l周内迅速缓解症状,并使嗜酸细胞恢复正常。病情可有反复,但预后良好。结论 EG患者临床和内镜表现无特异性,内镜下黏膜活检和腹水嗜酸粒细胞增多是诊断的关键,治疗以糖皮质激素为主。
Objective To investigate the clinical characteristics,diagnosis, therapy and prognosis of eosinophilic gastroenteritis （EG）.Methods 7 patients diagnosed as EG were studied. The data concerning the medicalhistory, clinical manifestations, laboratorytests, endoscopic test, pathological examination and therapy. Results EG symptoms of the patients were stomachache,The patients with mucosal type usually had abdominal pain,bloating,nausea.Bowl obstruction occurred generally in patients diagnosed as muscular type with or without abdominal pain.Abdominal pain,bloating and ascitas occured predominantly in those with serosal type.Increased peripheral eosinophil count was noted in 5 cases. Endoscopic examination revealed edema,erosion, hemorrhage and ulcer. Eosinophilic infiltration in the mucosa was confirmed by pathology. Glucocorticoid therapy could relieve symptoms and eosinophilia.Symptoms probably recur by good prognosis.Conclusion Clinical and endoscopic presentations are not specific.therefore the presence of eosinophilia in peripheral blood and ascites indicate the diagnosis.Steroid therapy is better than other therapy for the disease.
出处
《中国现代药物应用》
2011年第2期34-35,共2页
Chinese Journal of Modern Drug Application
关键词
嗜酸细胞性胃肠炎
临床表现
诊治
Eosinophilic gastroenteritis
Clinical manifestations
Diagnosis
