摘要
目的:明确 B M Ps 与外周神经的关系。方法:用原位杂交方法观察 B M P2,3,4,5 的m R N A在三叉神经中的表达。结果:在外周神经(三叉神经)中均有 B M P2,3,4,5 m R N A 分布, B M P2,3,4,5 的分布主要位于构成神经纤维髓鞘的雪旺细胞中;此外发现 B M P2 在部分神经纤维中也有表达。结论:首次确定了 B M P2,3,4,5 在外周神经中的表达和分布,揭示了 B M P2,3,4,5可能在外周神经的发育和再生以及形态结构的维持中发挥着调控作用。
bjective:To elucidate the relationship between BMPs and peripheral nerve.Method: In situ hybridization method was applied to detect the mRNA transcription and distribution of BMP2,3,4 and 5 in the trigeminal nerve.Results:The myelin sheaths of Schwann cells of trigeminal nerve were BMP2,3,4 and 5 positively stained,the nerve fibers of trigeminal nerve showed only BMP2 positive staining.Conclusion:BMP2,3,4 and 5 might be involved in the modulation of the development,regeneration and structure maintenance of peripheral nerve.
出处
《实用口腔医学杂志》
CAS
CSCD
北大核心
1999年第5期326-328,共3页
Journal of Practical Stomatology