摘要
目的：探讨影响婴幼儿迁延性腹泻病发病及预后的高危因素。方法：选取2007年1月-2009年12月收住儿内科符合诊断标准的病例76例,以同期急性腹泻病患儿60例作对照,经条件Logistic回归分析筛选影响其发病的危险因素。结果：影响其发病的危险因素有5个,即营养不良（OR=6.073）、贫血（OR=2.505）、1岁以下婴儿（OR=2.125）、使用抗生素（OR=1.091）、非母乳喂养（OR=0.329）。影响其预后的危险因素有4个,即营养不良（OR=7.286）、体液免疫异常（OR=6.873）、肠外感染（OR=0.276）、病程（OR=0.062）。结论：对小于1岁婴儿,预防及纠正营养不良、合理使用抗生素、大力提倡母乳喂养可降低婴幼儿迁延性腹泻病发生;对急性腹泻病患儿,早期合理治疗,加强护理,预防病程中再次感染,纠正体液免疫异常可明显改善预后。
Objective：To explore the high risk effect factors of occurrence and prognosis of infantile persistent diarrhea disease.Methods：76 infants according with diagnostic criteria who were in the hospital from January 2007 to December 2009 were selected,60 infants with acute diarrhea at the same period were selected as control group;conditional logistic regression analysis was used to screen the high risk effect factors of occurrence of infantile persistent diarrhea disease.Results：The high risk effect factors of occurrence of infantile persistent diarrhea disease included malnutrition（OR=6.073）,anemia（OR=2.505）,infants less than one year（OR=2.125）,antibiotic consumption（OR=1.091）,non-breast feeding（OR=0.329）;the high risk effect factors of prognosis of infantile persistent diarrhea disease included malnutrition（OR=7.286）,abnormal humoral immunity（OR=6.873）,extraintestinal infection（OR=0.276）,course of the disease（OR=0.062）.Conclusion：For the infants less than one year,preventing and correcting malnutrition,using antibiotics reasonably,advocating breast feeding actively may reduce the incidence of infantile persistent diarrhea disease;for the infants with acute diarrhea,enhancing nursing,preventing secondary infection during the course of the disease,correcting abnormal humoral immunity may improve the prognosis obviously.
出处
《中国妇幼保健》
CAS
北大核心
2011年第5期695-699,共5页
Maternal and Child Health Care of China
